Bioinformatics Engineer (Proteomics and Functional Genomics) London or Lausanne

We are looking for bioinformatics engineers with various levels of experience Mid through to Senior Principal Staff or equivalent levels.

We are here to advance human health by reimagining drug discovery with the power and pace of artificial intelligence.

The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured by better and faster drug discovery.

Our values exist in service of that future. We think theyll help us bring it closer too.

Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals while being a part of an inspiring and collaborative culture.

The world we want tomorrow is the one were building today. It starts with the culture at this company. It starts with you.

About Iso

Isomorphic Labs (IsoLabs) was founded in 2021 and is led by Sir Demis Hassabis. Our aim is to usher in a new era of biomedical breakthroughs and find cures for some of humanitys devastating diseases.

Our foundations are built on the success of Google DeepMinds AlphaFold but we didnt stop there! We are continuing to develop and implement stateoftheart technologies as we move towards our goal of dramatically accelerating and improving the process of designing and bringing new medicines to patients.

We have built a worldleading drug design engine comprising foundational AI models that are capable of working across multiple therapeutic areas and drug modalities. The company is continually innovating on model architecture and developing cuttingedge capabilities to advance rational drug design.

Your impact

This is an exciting opportunity for you to work on a greenfield MLbased software platform and ambitious Computational Biology research programme that will transform the biopharmaceutical world as we know it.

Working in a highly creative iterative environment you will be partnering with leading engineers scientists and ML researchers to build the critical platform driving this transformation. This is a newly created role and you will need to use your previous experience and show initiative in order to fully carve out your contribution.

What you will do

• Largescale biostatistical analysis and harmonisation of proteomics datasets.
• Implement and apply tools and methodologies for mass spectrometry proteomics.
• Implement and apply tools and methodologies for functional analysis (e.g. pathway analysis gene set enrichment analysis protein domain analysis proteinprotein interaction networks).
• Develop and operate bioinformatics pipelines for functional genomics and proteomics.
• Develop and curate robust data models and integration strategies to ensure data consistency quality and interoperability.
• Collaborate with computational biology and chemistry groups providing guidance and support for their initiatives.
• Provide training and guidance on proteomics functional genomics data resources and analysis tools to the organization.

Skills and qualifications

Essential

• Experience with large scale data harmonisation and normalisation.
• Experience working with proteomics data (e.g. mass spectrometry data analysis pipelines).
• Experience working with genomics data (e.g. variant calling RNAseq analysis).
• Knowledge of functional analysis tools and methodologies.
• Proficiency in programming languages like Python or R with experience developing bioinformatics pipelines.
• Knowledge of network analysis methodologies.
• PhD degree in Bioinformatics Computational Biology or a related field or equivalent practical experience.

Nice to have

• Knowledge of the pharmaceutical industry ideally with a focus on drug discovery
• Experience working with cloud computing environments.
• Experience with workflow management systems (e.g. nextflow snakemake).
• Exposure to machine learning concepts and their application in functional genomics and proteomics.
• Exposure to data curation.
  
  
  

Culture and values

We are guided by our shared values. Its not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it.

Thoughtful
Thoughtful at Iso is about curiosity creativity and care. It is about good people doing good rigorous and futuremaking science every single day.

Brave
Brave at Iso is about fearlessness but its also about initiative and integrity. The scale of the challenge demands nothing less.

Determined
Determined at Iso is the way we pursue our goal. Its a confidence in our hypothesis as well as the urgency and agility needed to deliver on it. Because disease wont wait so neither should we.

Together
Together at Iso is about connection collaboration across fields and catalytic relationships. Its knowing that transformation is a group project and remembering that what were doing will have a real impact on real people everywhere.

Creating an extraordinary company

We believe that to be successful we need a team with a range of skills and talents. Were building an environment where collaboration is fundamental learning is shared and every employee feels supported and able to thrive. We value unique experiences knowledge backgrounds and perspectives and harness these qualities to create extraordinary impact.

We are committed to equal employment opportunities regardless of sex race religion or belief ethnic or national origin disability age citizenship marital domestic or civil partnership status sexual orientation gender identity pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation please do not hesitate to let us know.

Hybrid working

Its hugely important for us to share knowledge and build strong relationships with each other and we find it easier to do this if we spend time together in person. This is why we follow a hybrid model and would require you to be able to come into the office 3 days a week (currently Tuesday Wednesday and one other day depending on which team youre in). If you have additional needs that would prevent you from following this hybrid approach wed be happy to talk through these if youre selected for an initial screening call.

Please note that when you submit an application your data will be processed in line with our .

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