Research Associate, PRISM Lab (Production Environment)
Research Associate, PRISM Lab (Production Environment)
Employer Active
Job Alert
You will be updated with latest job alerts via email
Share
Job Alert
You will be updated with latest job alerts via email
Job Description
General information
Description & Requirements
The PRISM technology allows us to routinely profile over 900 DNAbarcoded cell lines with hundreds of therapeutics in a pooled format much more rapidly than traditional cell line screening. The power of PRISM is realized through our vast understanding of the underlying genomic features of the cell lines: every single therapeutic tested with PRISM delivers not only viability information but also a wealth of genomic correlations and multivariate analyses to provide a holistic understanding of drug behavior. We use these features to help identify offtarget effects patient populations biomarkers of response and of resistance and much more. We collaborate with many large pharmaceutical companies through the Dependency Map Consortium biotech companies academic labs and internally with labs at the Broad Institute to help discover new cancer therapeutics at all phases of the drug discovery process.
WHAT YOU SHOULD KNOW:
Please note that this is a pipeline requisition for 2 opportunities within our PRISM Lab as either a Research Associate I or Research Associate II with immediate openings. These roles are highvolume production process development roles and you will not have an opportunity to contribute to any publications in this role.Our candidate preference is for individuals that are not looking to return to graduate school in the next 12 years.
These positions create the exciting opportunity to join our multidisciplinary team to assist with highthroughput cell line screening and to contribute to our goal of finding novel cancer treatments.
For both roles candidates will bring basic experience with working in a sterile tissue culture lab environment as well as basic molecular biology techniques and a high attention to detail.
- High Throughput Screening (HTS) team to support our largescale screening projects by assisting with cell culture and cell plating working with automated and semiautomated equipment to execute our cellbased viability assays maintaining inventories of compounds and chemicals used in our assays and performing qualitycontrol assessments of our workflows and equipment.
- Cell Pooling team The PRISM technology allows us to routinely profile over 900 DNAbarcoded cell lines with hundreds of therapeutics in a pooled format much more rapidly than traditional cell line screening. The successful candidate will play a crucial role in supporting our scientific research with routine cell culture and molecular biology tasks as the main responsibility of this role. Research assistants in the PRISM lab routinely culture up to 30 cell lines at a time mixing 25 cell lines together for our pools to be used in our screens ensuring our cell lines are properly stored and maintaining a sterile environment within the lab.
MINIMUM QUALIFICATIONS:
- At least a B.S. in Biology Biomedical Engineering Molecular Biology or related fields
- At least 1 year experience in a biological research environment and experience with mammalian cell culture
- Knowledge of highthroughput screening and automation and/or experience working in a high throughput production setting is desired but not required
- Experience with basic molecular biology techniques including PCR DNA extractions etc.
- Must have excellent written documentation and oral communication skills
- Must possess strong interpersonal organizational and analytical skills including the ability to handle a variety of tasks in a fastpaced environment
- Strong attention to detail time management skills and the ability to maintain accurate records and documentation.
Required Experience:
IC
Employment Type
Full Time
