Associate Scientist II or Scientist, Antibody Sequencing & Analysis
Associate Scientist II or Scientist, Antibody Sequencing & Analysis
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1 Vacancy
Job Description
The Biotherapeutics and Genetics Medicine department within Discovery Research is seeking a highly motivated research scientist to join the Molecular Core team at AbbVie Bioresearch Center (ABC). The ABC site based in Worcester MA offers the unique setting where Biotherapeutics discovery development and manufacturing coexist in one location. The Molecular Core interacts with multidisciplinary groups across AbbVie focused on developing therapies for Immunology Neurology and Oncology diseases. We utilize innovative approaches and bestinclass platforms to enable successful antibody discovery against complex targets.
As an integral part of the group the ideal candidate will:
- Execute molecular biology workflows including NextGeneration Sequencing (NGS) to capture antibody sequences from hybridoma single B cell immune repertoires and in vitro sources enabling discovery of antibodies as well as novel therapeutic formats
- Perform molecular cloning and contribute to technology development in the molecular biology group
- Further optimize NGS workflow troubleshoot when needed and identify areas for improvement
- Manage inventory and supplies and ensure routine maintenance of NGS and other lab instruments is performed
- Perform data analyses and report generation (bioinformatics experience is a plus)
- Analyze and document results placing data in proper scientific context through review of relevant literature and report findings at team meetings
- Demonstrate scientific excellence through dedication to multiple projects in a fastpaced multidisciplinary environment
- Exhibit a cando attitude with excellent interpersonal and communication skills to multiple teams across different functional areas
Qualifications :
Qualifications:
- BS or MS in Molecular Biology Biochemistry Bioinformatics or a related field with typically 37 years (BS) or 05 years (MS) of relevant industry or academic experience
- Understanding and proficiency in molecular biology techniques (e.g. PCR molecular cloning plasmid design)
- Experience with the application of DNA sequencing techniques (NGS and Sanger) for the identification of V(D)J sequences and analysis for antibody discovery
- Ability to improve and streamline existing processes
- Familiarity with immunology and antibody genetics
- Strong attention to quality and details when exercising organizational documentation and communication skills
- Proven flexibility to deal with changing timelines and shifting work priorities
- Competency with software programs including DNA analysis (Geneious Sequencher) and MS Office (Excel PowerPoint Word)
Desirable:
- Prior experience in bioinformatics and automation is highly desired
- Experience with antibody repertoire analysis using 10X Genomics
- Experience with mammalian cell culture aseptic technique and transient transfection
- Experience in immunoassays using techniques like ELISA and flow cytometry
Position will be hired based on level of experience Associate Scientist II or Scientist I or Scientist II
Additional Information :
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location and we may ultimately pay more or less than the posted range. This range may be modified in the future.
We offer a comprehensive package of benefits including paid time off (vacation holidays sick) medical/dental/vision insurance and 401(k) to eligible employees.
This job is eligible to participate in our shortterm incentive programs.
Note: No amount of pay is considered to be wages or compensation until such amount is earned vested and determinable. The amount and availability of any bonus commission incentive benefits or any other form of compensation and benefits that are allocable to a particular employee remains in the Companys sole and absolute discretion unless and until paid and may be modified at the Companys sole and absolute discretion consistent with applicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity driving innovation transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
US & Puerto Rico only to learn more visit & Puerto Rico applicants seeking a reasonable accommodation click here to learn more:
No
Employment Type :
Fulltime
Employment Type
Full-time
