The Biomedical Modeler performs advanced pharmacometric modeling and/or statistical analysis to support laboratory and/or clinical research projects and performs tasks related to the project independently and in addition to widely accepted approaches to data analysis may utilize novel approaches. They will assist with performing manuscript preparation to disseminate results of the modeling in peerreviewed publications.
The Senior Biomedical Modeler performs advanced pharmacometric modeling and/or statistical analysis to support laboratory and/or research projects. Performs tasks related to the project independently and in addition to widely accepted approaches to data analysis may utilize novel approaches. Performs manuscript preparation to disseminates results of the modeling in peerreviewed publications. Performs training of advanced modeling techniques to individuals as assigned by their supervisor.
The Center for Translational Pharmacology (CTP) at St. Jude Childrens Research Hospital has two open positions for highly motivated and creative individuals at the Senior Biomedical Modeler and Biomedical Modeler level within the Department of Pharmacy and Pharmaceutical Sciences. The CTP is the nexus for clinical pharmacology at St. Jude where the clinical enterprise has expanded beyond oncology to programs that include nonmalignant hematology cell therapy infectious diseases neurologic diseases epidemiology and psychology.
Scientists with expertise in innovative pharmacometric and statistical approaches for pharmacokinetic and pharmacodynamic data analysis are encouraged to apply. The biomedical modeling group is integral to clinical trial design and interpretation and scientists are expected to contribute to manuscript preparation with appropriate credit on publications. Additional opportunities for scholarship through novel modeling approaches are encouraged and CTP scientists will have the opportunity for continued professional development through training and participation in scientific conferences. The CTP provides a highly interactive environment with collaborative opportunities for meaningful contributions to the design of all pharmacology aspects within the context of phase 0 phase I and phase II clinical trials. CTP biomedical modelers will interact with faculty in the Department of Pharmacy and Pharmaceutical Sciences and clinicians across all clinical research programs.
Biomedical Modeler
Job Responsibilities:
- Provide pharmacometric expertise to researchers as designated by collaboration areas in all aspects of conducting pharmacometric and/or statistical analyses for basic translational and/or clinical studies. Assists with acquiring or acquires the data for modeling and verifies the data prior to modeling.
- Design coordinate supervise and implement quality control procedures for both clinical and preclinical research data. Develop appropriate methods to ensure the validity of pharmacometric research data. Works with Lab database to ensure validity of pharmacometric research data.
- Assist in the preparation of pharmacometric results for meeting abstracts posters and peerreviewed manuscripts. May serve as a coauthor or in select cases as a primary author on biomedical modeling related publications.
- Provides education and training in pharmacometric techniques to individuals as assigned by the supervisor.
- Performs other related duties as assigned in order to meet the goals and objectives of the department and institution.
Minimum Education and/or Training:
- Bachelors degree in mathematics engineering or computer science with advanced training in pharmacometrics and/or quantitative systems biology modeling is required.
- Masters degree or PhD in mathematics biomedical engineering or related field with advanced training in pharmacometrics and/or quantitative systems biology modeling is preferred.
Minimum Experience:
- Four (4) years of relevant experience in pharmacometrics biostatistics and/or a relevant research field.
- With a PhD three (3) years of relevant experience in a pharmacometric or biostatistics and/or a relevant research field is required.
- Experience in standard pharmacometric and statistical methods software and study design is preferred.
Compensation for Biomedical Modeler: $94640.00/yr. $169520.00/yr.
Senior Biomedical Modeler
Job Responsibilities:
- Provide pharmacometric expertise to researchers as designated by collaboration areas in all aspects of conducting pharmacometric and/or statistical analyses for basic translational and/or clinical studies. Assists with acquiring or acquires the data for modeling and verifies the data prior to modeling.
- Understand integrate and use widely accepted as well as novel approaches to pharmacometric modeling and statistical analysis (e.g. R Matlab).
- Utilize routine pharmacometric software (e.g. ADAPT NONMEM Monolix WinNonlin SimCYP PK Sim MOBI GastroPlus) to conduct noncompartmental as well as compartmental analyses.
- Introduce novel and stateoftheart pharmacometric modeling techniques as project warrants.
- Participate in the development of software interfaces for clinical programs necessary for pharmacokinetic and drug dosage adjustment for clinical protocols.
- Design coordinate supervise and implement quality control procedures for both clinical and preclinical research data. Develop appropriate methods to ensure the validity of pharmacometric research data. Works with Lab database to ensure validity of pharmacometric research data.
- Prepare pharmacometric results for meeting abstracts posters and peerreviewed manuscripts and serve as a coauthor or in select cases as a primary author on biomedical modeling related publications.
- Provide pharmacometric expertise to researchers as designated by collaboration areas in all aspects of conducting pharmacometric and/or statistical analyses for basic translational and/or clinical studies. Assists with acquiring or acquires the data for modeling and verifies the data prior to modeling.
- Understand integrate and use widely accepted as well as novel approaches to pharmacometric modeling and statistical analysis (e.g. R Matlab).
- Utilize routine pharmacometric software (e.g. ADAPT NONMEM Monolix WinNonlin SimCYP PK Sim MOBI GastroPlus) to conduct noncompartmental as well as compartmental analyses.
- Introduce novel and stateoftheart pharmacometric modeling techniques as project warrants.
- Participate in the development of software interfaces for clinical programs necessary for pharmacokinetic and drug dosage adjustment for clinical protocols.
- Design coordinate supervise and implement quality control procedures for both clinical and preclinical research data. Develop appropriate methods to ensure the validity of pharmacometric research data. Works with Lab database to ensure validity of pharmacometric research data.
- Prepare pharmacometric results for meeting abstracts posters and peerreviewed manuscripts and serve as a coauthor or in select cases as a primary author on biomedical modeling related publications.
- Provides education and training in pharmacometric techniques to individuals as assigned by the supervisor.
- Perform other duties as assigned to meet the goals and objectives of the department and institution.
- Maintains regular and predictable attendance.
Minimum Education and/or Training:
- Bachelors degree in mathematics engineering or computer science with advanced training in pharmacometrics and/or quantitative systems biology modeling in required.
- Masters degree or PhD in mathematics biomedical engineering or related field with advanced training in pharmacometrics and/or quantitative systems biology modeling is preferred.
Minimum Experience:
- Five (5) years of relevant experience in pharmacometric or biostatistics and/or a relevant field of research.
- Experience in standard and advanced pharmacometric and statistical methods software and study design is preferred.
Compensation for Senior Biomedical Modeler: $104000.00/yr. $186160.00/yr.
Compensation
In recognition of certain U.S. state and municipal pay transparency laws St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets experience and training licensure and certifications and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $104000 $186160 per year for the role of Biomedical Modeler or Senior Biomedical Modeler & Pharmacometrician.
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Required Experience:
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