Process Dev Engineering Scientist
Process Dev Engineering Scientist
Employer Active
Job Alert
You will be updated with latest job alerts via email
Share
Job Alert
You will be updated with latest job alerts via email
Job Description
Job Description
General Summary:
Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people living with serious diseases with a focus on specialty markets. We invest in diseases where there is a significant unmet need and we can have a transformative impact for patients not just an incremental benefit. We invest the majority of our resources in research and development (R&D) to discover new medicines because we believe the true value in our industry is unleashed through scientific innovation. Cell and genetic therapies represent two rapidly emerging therapeutic modalities with the potential to treatand even cureseveral of the diseases Vertex is focused on including sickle cell disease and type 1 diabetes. Our Cell and Genetic Therapies (CGT) teams bring together the best biology technologies and enhanced manufacturing capabilities to ensure we bring these cuttingedge transformative therapies to patients as quickly as possible.
CGT is seeking a Scientist to join our Process Development team to support our media development effort. The focus of this positionis to contribute to the innovative stem cell culture medium development and optimization for cell and gene therapy applications collaborating with high performing teams. This position will provide opportunities to independently lead scientific innovation projects to advance media optimizations with impactful deliverables on CoG reduction for cell therapy commercial scale manufacturing as well as process robustness improvement through more advanced process fundamental understandings. The position will be based in Boston MA.
Duties and Responsibilities:
- Lead the design and of experiments to evaluate new medium components and supplements through assessment of cell culture performance.
- Apply basic and advanced analytical tools including spent media analysis and omics for indepth fundamental understanding of the process as well as continuous optimization of stem cell culture medium.
- Contribute to the establishment and utilization of high throughput small scale screening platforms.
- Apply Design of Experiment (DOE) principles for medium development and optimization.
- Collaborate with crossfunctional teams aligning on project goals sharing results and fostering a collaborative working environment.
- Ensure data integrity by timely completion of phaseappropriate documentation including electronic notebook system development protocols and technical reports to support future technology transfers and regulatory filings.
- Ensure compliance with lab safety procedures.
- Lead by example work closely with the team in the lab and conduct hands on experiments.
- Mentor and support junior team members to independently plan and design experiments.
Minimum Requirements
- Degree in Stem Cell Biology Chemical/Biochemical/Biomedical Engineering Life Sciences or related discipline.
- PhD with a minimum of 03 years of relevant industry work experience or a BS with 6years of industry experience or a MS with 4 years of relevant industry experience.
- Strong fundamental knowledge and previous experience of medium development and mammalian cell culture (stem cell culture knowledge and experience are preferred) as well as knowledge of recent advances and challenges in the field.
- Solid knowledge and experience on DoE principled experimental design and .
- Strong fundamental knowledge and experience on bioreactors across scales (experience with high throughput and automatic cell culture platforms is highly preferred).
- Must have a working knowledge of cGxP.
- Excellent verbal and written communication skills.
- Ability to handle multiple tasks while meeting timelines and adapting to changing priorities.
- Excellent organizational skills and high attention to detail.
- Participate in weekend work rotation with the broader team.
- Authorized to legally work in the US.
Pay Range:
$105600 $158400Disclosure Statement:
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors including skills competencies experience and other jobrelated factors permitted by law.
At Vertex our Total Rewards offerings also include inclusive marketleading benefits to meet our employees wherever they are in their career financial family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical dental and vision benefits to generous paid time off (including a weeklong company shutdown in the Summer and the Winter) educational assistance programs including student loan repayment a generous commuting subsidy matching charitable donations 401(k) and so much more.
Flex Designation:
OnSite DesignatedFlex Eligibility Status:
In this OnSite designated role you will work five days per week onsite with ad hoc flexibility.
Note: The Flex status for this position is subject to Vertexs Policy on Flex @ Vertex Program and may be changed at any time.
Company Information
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and nondiscrimination for all employees and qualified applicants without regard to a persons race color sex gender identity or expression age religion national origin ancestry ethnicity disability veteran status genetic information sexual orientation marital status or any characteristic protected under applicable law. Vertex is an EVerify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager or contact Talent Acquisition at
Employment Type
Full-Time
