Principal Research Scientist II Phys Chem
Principal Research Scientist II Phys Chem
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Salary Not Disclosed
1 Vacancy
Job Description
The Structural Biology Group at AbbVie Headquarters in Lake County Illinois is seeking a highly motivated scientist with extensive infrastructure experience and people leadership skills to join our StructureBased Drug Discovery (SBDD) team. The ideal candidate will have a proven track record in SBDD using Xray crystallography CryoEM and SAXS along with a passion for building infrastructure in an industrial pharmaceutical environment. The successful candidate will work with and lead a centralized multidisciplinary Structural Biology team that supports global Discovery Research across AbbVies portfolio. In addition to driving SBDD this candidate will play a key role in shaping the groups scientific infrastructure by ensuring technology integration and expansion and developing data management systems to accelerate drug discovery.
Key Responsibilities:
- Determine Xray crystal structures of proteinligand complexes in highthroughput mode to aid medicinal chemistry design and partner with biologists molecular modelers and medicinal chemists to drive SBDD.
- Advance infrastructure initiatives to enhance structural biology workflows improve data management and increase crossfunctional accessibility to improve efficiency and scientific impact. Design and implement robust scalable systems for automated data analysis.
- Stay at the forefront of structural biology technologies bringing in novel capabilities that enhance the scientific infrastructure and enable innovation at AbbVie.
- Provide handson and strategic leadership in CryoEM and SAXS applications to support diverse drug discovery programs.
- Lead and mentor a team of highperforming scientists in areas of protein crystallization Xray crystallography CryoEM SAXS and infrastructure development.
- Aid construct design efforts for structural biology efforts.
- Utilize cheminformatics tools and manipulate scripts for use across mixed computing platforms.
- Maintain accurate and timely records of experimental results.
- Communicate results and interpretative analysis through highimpact presentations and reports to internal stakeholders and at external scientific forums. Publish in peerreviewed journals as appropriate.
- Critically evaluate scientific literature and adopt novel technologies that facilitate structurebased drug discovery at AbbVie.
Qualifications :
- PhD in Chemistry Biochemistry Biophysics or a related field.
- 12 years of structural biology experience with a requirement for industry experience.
- Deep expertise in protein crystallization and structure determination and analysis using Xray and CryoEM.
- Familiarity with structurebased drug design strategies.
- Demonstrated experience in strategizing executing and managing scientific infrastructure.
- Proficiency in programming and scripting skills with the ability to work across various computing environments.
- Excellent organizational communication and leadership skills.
- Proven ability to work independently as well as part of a highly collaborative interdisciplinary team.
- Effective written and verbal communication skills.
- Ability to manage multiple projects and adapt quickly to evolving priorities in a fastpaced environment.
Additional Information :
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location and we may ultimately pay more or less than the posted range. This range may be modified in the future.
We offer a comprehensive package of benefits including paid time off (vacation holidays sick) medical/dental/vision insurance and 401(k) to eligible employees.
This job is eligible to participate in our shortterm incentive programs.
This job is eligible to participate in our longterm incentive programs
Note: No amount of pay is considered to be wages or compensation until such amount is earned vested and determinable. The amount and availability of any bonus commission incentive benefits or any other form of compensation and benefits that are allocable to a particular employee remains in the Companys sole and absolute discretion unless and until paid and may be modified at the Companys sole and absolute discretion consistent with applicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity driving innovation transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
US & Puerto Rico only to learn more visit & Puerto Rico applicants seeking a reasonable accommodation click here to learn more:
No
Employment Type :
Fulltime
Employment Type
Full-time
