Sr Expert Science Technology Product Sciences - Cell Therapy Analytical Development

Band

Level 4

Job Description Summary

Internal Title: Senior Expert Science & Technology
Location: East Hanover NJ United States (OnSite)
This position will be located at East Hanover site and will not have the ability to be located remotely.

We are seeking a highly skilled and driven Senior Expert in Product Sciences to join our team in advancing transformative cell therapy products. Reporting to the Director of Product Sciences this role focuses on driving product characterization efforts incorporating immunological principles and developing innovative scientific approaches to solve complex challenges in the cell therapy space. As a senior bench scientist you will leverage your expertise in immunology cell biology and advanced analytical methods to generate actionable product insights and support the development of safe and efficacious cell therapy products that meet our target profiles. This role requires handson work in a fastpaced environment applying scientific rigor and industry knowledge to enable datadriven decisionmaking.

Job Description

Key Responsibilities:

• Develop and refine advanced product characterization methods to assess quality attributes of cell therapy products intermediates and starting material.
• Design and execute innovative assays to assess T cell function lineage cytokine production proliferation cytotoxicity memory composition differentiation exhaustion metabolic profiling and omics profiling. Qualify appropriate assay parameters to ensure characterization assays are fit for purpose.
• Apply critical thinking skills to identify the right scientific questions aligned with product development goals. Independently design and execute experiments to address foundational and applied questions leveraging immunological principles and cell therapy expertise.
• Ensure effective data collection management and analysis to drive datadriven decisionmaking processes. Support regulatory filing by providing highquality data technical reports and scientific rationale.
• Collaborate with teams across Analytical Development Process Development Regulatory CMC Biostatistics and Data Sciences to drive cell therapy programs forward.
• Share scientific knowledge and assay development expertise to inform decisions on attribute criticality specification setting and control strategies.
• Stay up to date on advances within immunology cell therapy sciences and analytical technologies.
• Work proactively (i.e. using statistical methodologies) to address challenges in manufacturing success and clinical outcomes through product and process understanding.

Requirements:

• Ph.D. in Immunology Cell Biology or a relevant field strongly preferred. Masters degree with significant industry experience in cell therapy product characterization may be considered.
• A minimum of 5 years of posteducational handson experience in developing Tcell characterization assays.
• Demonstrated track record of benchlevel assay development and product characterization in T cellbased therapies or similar therapeutic modalities.
• Deep knowledge of T cell biology and immunology. Familiarity with advanced analytical techniques such as flow cytometry cellbased assays ELISA q/dPCR Omics imaging cytometry and multiplex technologies.
• Strong problem solving and trouble shooting skills in a dynamic and fastpaced environment.
• Exceptional communications scientific writing and presentation skills.

Desirable Requirements:

• Practical experience in statistics
• Experience contributing to regulatory filings (IND BLA) with data packages related to cell therapy product characterization.

Novartis Compensation and Benefit Summary: The pay range for this position at commencement of employment is expected to be between: $114100 and $211900/year; however while salary ranges are effective from 1/1/25 through 12/31/25 fluctuations in the job market may necessitate adjustments to pay ranges during this period. Further final pay determinations will depend on various factors including but not limited to geographical location experience level knowledge skills and abilities. The total compensation package for this position may also include other elements including a signon bonus restricted stock units and discretionary awards in addition to a full range of medical financial and/or other benefits (including 401(k) eligibility and various paid time off benefits such as vacation sick time and parental leave) dependent on the position offered. Details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired employee will be in an atwill position and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time including for reasons related to individual performance Company or individual department/team performance and market factors.

EEO Statement:

The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment hiring training promotion or other employment practices for reasons of race color religion gender national origin age sexual orientation gender identity or expression marital or veteran status disability or any other legally protected status. We strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Accessibility and reasonable accommodations

The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If because of a medical condition or disability you need a reasonable accommodation for any part of the application process or in order to perform the essential functions of a position please send an email to calland let us know the nature of your request and your contact information. Please include the job requisition number in your message.

Range

$114100.00 $211900.00

Skills Desired

Coaching Skills Data Science Environment Experiments Design Health And Safety (Ehs) Laboratory Equipment Manufacturing Process Materials Science Process Simulation Sop (Standard Operating Procedure) Technical Writing Waterfall Model