drjobs Principal Scientist Cardiovascular Disease in Bioscience

Principal Scientist Cardiovascular Disease in Bioscience

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1 Vacancy
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Job Location drjobs

Gaithersburg, MD - USA

Monthly Salary drjobs

$ 172672 - 259008

Vacancy

1 Vacancy

Job Description

Do you have expertise and a strong scientific reputation in cardiovascular research Are you excited by a role where you will provide global scientific leadership within your area of expertise to accelerate innovative science and turn ideas into lifechanging medicines Join us to be part of the discovery of future treatments for Cardiovascular Renal and Metabolic diseases. We are now recruiting a Principal Scientist with cardiovascular expertise to the Bioscience department in Early Cardiovascular Renal and Metabolism (Early CVRM) one of AstraZenecas three main therapeutic areas. In the Bioscience department we focus on identifying and validating new drug targets and delivering preclinical data to projects across all phases of drug discovery and development. As the Principal Scientist you are a key player in the global CVRM community and in the cardiovascular division influencing pipeline projects scientific direction and capabilities. You will work at the forefront of cardiovascular research and continue to demonstrate scientific leadership through highquality publications conference presentations and by building networks and collaborations with key external authorities. The role will be placed at AstraZenecas R&D site in Gaithersburg US. Here you will be part of an openminded and creative working atmosphere based on collaboration and innovation. You will report to the Head of Bioscience Cardiovascular and be part of the bioscience cardiovascular leadership team.

Accountabilities

  • Serve as a scientific leader and authority in the cardiovascular area (focus on cardiomyopathy cardiometabolic disease and/or atherosclerosis). Bring expertise in heart function and pathophysiology.
  • Serve as bioscience/pharmacology lead and project lead for early pipeline projects.
  • Independently identify and explore novel drug targets and champion these to become new drug projects.
  • Drive innovation and scientific excellence in the cardiovascular area.
  • Propose and drive development of cardiovascular models/assays.
  • Serve as a member of the Bioscience Cardiovascular Leadership team.
  • Accountable for longterm development of the Bioscience department in close collaboration with other senior leaders in Bioscience.
  • Collaborate closely with colleagues in Early CVRM and in other essential functions to drive the cardiovascular pipeline.
  • Build and maintain a network to key internal and external partners and leading research institutions.
  • Build scientific leadership for AstraZeneca by publishing scientific papers and presenting at conferences.

Essential Skills/Experience

  • PhD M.D. or equivalent academic merits in the cardiovascular field with specific focus on cardiomyopathy or cardiometabolic disease.
  • Minimum of 4 years of industry experience.
  • Strong scientific background and understanding of cardiac biology and disease and the link between metabolic aspects and cardiovascular risk
  • Strong leadership capabilities
  • Proven track record to lead sophisticated collaborations and partnerships
  • Strong experience in in vitro and in vivo work within the cardiovascular area
  • Strong publication track record in the cardiovascular area
  • Excellent communication and networking skills
  • Outstanding teamworking skills and a consistent record of working collaboratively to ensure scientific excellence and timely progression of projects

Desirable Skills/Experience

  • Postdoc in a relevant area
  • Experience in working with atherosclerosis and expertise in microvascular dysfunction and plaque formation
  • Extensive drug discovery experience and preferably with experience in progressing drug targets to clinical testing

When we put unexpected teams in the same room we fuel bold thinking with the power to inspire lifechanging medicines. Inperson working gives us the platform we need to connect work at pace and challenge perceptions. Thats why we work on average a minimum of three days per week from the office. But that doesnt mean were not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our outstanding and bold world.

Be encouraged and supported to think creatively in our dynamic environment. Here we are free from fear of failure free to ask the right questions and make ambitious decisions. It takes resilience to embody our entrepreneurial spirit. For those who flourish with experimentation youll get to work with knowns and unknowns. Exploring without limits.

The annual base pay for this position ranges from $172672 $259008USD Annual.Hourly and salaried nonexempt employees will also be paid overtime pay when working qualifying overtime pay offered may vary depending on multiple individualized factors including market location jobrelated knowledge skills and experience. In addition our positions offer a shortterm incentive bonus opportunity; eligibility to participate in our equitybased longterm incentive program (salaried roles)to receive a retirement contribution (hourly roles) and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program 401(k) plan; paid vacation and holidays; paid leaves; and health benefits including medical prescription drug dental and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired employee will be in an atwill position and the Company reserves the right to modify base pay(as well as any other discretionary payment or compensation program) at any time including for reasons related to individual performance Company or individual department/team performance and market factors.

If your passion is science and you want to be part of a team that makes a bigger impact on patients lives then please apply no later than 16 May 2025.

For more information please contact Karin Jennbacken

Ready to make a difference Apply now!

Date Posted

23Apr2025

Closing Date

15May2025Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion starting with our recruitment process. We welcome and consider applications from all qualified candidates regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations please complete the section in the application form.

Required Experience:

Staff IC

Employment Type

Full-Time

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