Conjugation Scientist Biotherapeutic Engineering BS or MS
Conjugation Scientist Biotherapeutic Engineering BS or MS
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$ 85400 - 158600
1 Vacancy
Job Description
Band
Level 3Job Description Summary
Internal Title: Senior Scientist I#LIOnsite lab role
The Biologics Research Center (BRC) is seeking a highly motivated scientist with the skills and experience to contribute to advancing ADC to patients in need. This is a great opportunity to join a group dedicated to protein antibody drug/ antibody drug conjugate discovery. In this role you will be a member of several multidisciplinary teams in a variety of disease areas you will support the Novartis conjugation core and be a key player in advancing drug discovery projects.
*A proven track record of handson experience with conjugation chemistry and analytical assays are essential for this role*
Job Description
Key Responsibilities:
- Independently conjugate purify and characterize antibodydrug and/or oligonucleotide conjugates (ADCs/AOCs) using applicable instrumentation for linkerpayload conjugation and purification analytical techniques and characterization assays
- Coordinate the submission for supplementary biophysical characterization and interpret analytical results with area experts.
- Contribute to the analysis and synthesis of results design of new experiments and clear communication of scientific progress to project team(s); troubleshoot experiments optimize conjugation protocols and suggest mitigation strategies to meet project accelerated timelines.
- Work effectively as a member of crossfunctional teams to accomplish shared project goals.
- Contemporaneous and accurate documentation of experiments in ELN and registration databases
- Contribute to patents publications and technical reports
Essential Requirements:
- This is not a PhD level position
- Independently conjugate purify and characterize antibodydrug and/or oligonucleotide conjugates (ADCs/AOCs) using applicable instrumentation for linkerpayload conjugation and purification analytical techniques and characterization assays
- Coordinate the submission for supplementary biophysical characterization and interpret analytical results with area experts.
- Contribute to the analysis and synthesis of results design of new experiments and clear communication of scientific progress to project team(s); troubleshoot experiments optimize conjugation protocols and suggest mitigation strategies to meet project accelerated timelines.
- Work effectively as a member of crossfunctional teams to accomplish shared project goals.
- Contemporaneous and accurate documentation of experiments in ELN and registration databases
- Contribute to patents publications and technical reports
Desirable Requirements:
- Proficiency in any of the following: antibody engineering and characterization
- Experience with expressing purifying and characterizing hybridomas and recombinant antibodies
- Extended molecular biology expertise in assays such as cloning and qPCR
- Experience in cell binding and functional assays for antibody/ ADC/AOC characterization
- Experience with biological assays such as measuring cytotoxic activity for ADC characterization
- Ability to analyze experiments in related software such as Microsoft Excel including basic macro programing; FlowJo; Octet etc.
Company will not sponsor visas for this position.
Novartis is unable to offer relocation support for this role: please only apply if this location is accessible for you.
Novartis Compensation and Benefit Summary:
The pay range for this position at commencement of employment is expected to be between: $85400 and $158600/year; however while salary ranges are effective from 1/1/25 through 12/31/25 fluctuations in the job market may necessitate adjustments to pay ranges during this period. Further final pay determinations will depend on various factors including but not limited to geographical location experience level knowledge skills and abilities. The total compensation package for this position may also include other elements including a signon bonus restricted stock units and discretionary awards in addition to a full range of medical financial and/or other benefits (including 401(k) eligibility and various paid time off benefits such as vacation sick time and parental leave) dependent on the position offered. Details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired employee will be in an atwill position and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time including for reasons related to individual performance Company or individual department/team performance and market factors.
EEO Statement:
The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment hiring training promotion or other employment practices for reasons of race color religion gender national origin age sexual orientation gender identity or expression marital or veteran status disability or any other legally protected status. We strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.
Accessibility and reasonable accommodations
The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If because of a medical condition or disability you need a reasonable accommodation for any part of the application process or in order to perform the essential functions of a position please send an email to calland let us know the nature of your request and your contact information. Please include the job requisition number in your message.
Range
Skills Desired
Analytical Skill Analytical Skill Analytical Thinking Chemical Biology Chemistry Clinical Research Clinical Trials Collaboration Communication Skills Curiosity Data Data Analysis Design Of Experiments DetailOriented Diversity & Inclusion Drug Discovery Ethics Gene Therapy Immunology Laboratory Lifesciences Machine Learning (Ml) Mammalian Cell Culture Medical Research Molecular Biology 11 moreEmployment Type
Full-Time
