Scientist Functional Cancer Genomic
Scientist Functional Cancer Genomic
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Job Description
At Roche you can show up as yourself embraced for the unique qualities you bring. Our culture encourages personal expression open dialogue and genuine connections where you are valued accepted and respected for who you are allowing you to thrive both personally and professionally. This is how we aim to prevent stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche where every voice matters.
The Position
A healthier future. Its what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. Thats what makes us Roche.
This position is located within our Discovery Research Units within the Oncology Discovery organization dedicated to the discovery and development of novel cancer therapeutics. We collaborate closely with functions in Therapeutic Modalities Pharmaceutical Science as well as within the oncology therapeutic area to translate hypotheses into innovative therapeutics.
The Opportunity
Design and lead innovative research projects focused on target discovery and validation in cancer biology.
Apply cuttingedge functional genomic approaches including CRISPRbased screening to identify and characterize novel therapeutic targets.
Develop and optimize advanced 3D organoid models to investigate tumor biology and therapeutic responses.
Analyze largescale genomic proteomic and transcriptomic datasets to uncover key disease mechanisms and potential therapeutic vulnerabilities.
Collaborate closely with multidisciplinary teams including computational biologists translational scientists and clinical researchers to drive datadriven discoveries.
Present research findings at internal meetings scientific conferences and contribute to highimpact peerreviewed publications.
Stay at the forefront of emerging technologies and advancements in cancer biology to integrate the latest innovations into research programs
Who you are
You have a Ph.D. in Cancer Biology Molecular Biology Genetics or a related field and bring a strong background in at least one key disease area such as colorectal cancer lung cancer or breast cancer. Further you have proven expertise in functional genomics particularly CRISPR/Cas9based screening techniques and handson experience with 3D organoid culture systems and their application in disease modelling. Ideally you also bring a couple of years of postdoctoral or industry experience in oncology drug discovery or translational cancer research/biology. Familiarity with in vivo cancer models and their translational applications would also be of advantage. Further you have:
Strong proficiency in analysing genomic transcriptomic data using bioinformatics tools.
Advanced Flow Cytometry & Cell Sorting skill: Proficiency in multicolor flow cytometry including spectral flow and FACSbased cell isolation
Experience in cellbased assays for target validation (e.g. livecell imaging proliferation apoptosis migration and invasion assays)
Demonstrated track record of impactful scientific publications in peerreviewed journals.
Ability to work both independently and collaboratively in a dynamic and fastpaced research environment.
Excellent problemsolving communication and organizational skills.
Experience managing projects setting priorities and aligning research goals with translational applications
Strong problemsolving mindset with a willingness to integrate emerging technologies into research workflows
Unwavering focus collaborative teamwork and exceptional delivery are key behaviours that drive our mission of doing now what patients need next. Together we can be transformative.
If you are passionate about contributing to a committed team and have the dedication to partnership and innovation Roche is the place for you! Every role at Roche plays a part in making a difference in patients lives. Apply now and join us in making an impact!
Who we are
A healthier future drives us to innovate. Together more than 100000 employees across the globe are dedicated to advance science ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities foster creativity and keep our ambitions high so we can deliver lifechanging healthcare solutions that make a global impact.
Lets build a healthier future together.
Basel is the headquarters of the Roche Group and one of its most important centres of pharmaceutical research. Over 10700 employees from over 100 countries come together at our Basel/Kaiseraugst site which is one of Roches largest sites. Read more.
Besides extensive development and training opportunities we offer flexible working options 18 weeks of maternity leave and 10 weeks of gender independent partnership leave. Our employees also benefit from multiple services on site such as childcare facilities medical services restaurants and cafeterias as well as various employee events.
Roche is an Equal Opportunity Employer.
Employment Type
Full-Time
