Postdoc Scholar
Postdoc Scholar
Employer Active
Job Alert
You will be updated with latest job alerts via email
Share
Job Alert
You will be updated with latest job alerts via email
Job Description
Department Overview
The Carbone Lab at Oregon Health & Science University is seeking a highly motivated and skilled junior Postdoctoral Scholar to join our team. This position offers a unique opportunity to engage in both wet lab and computational research with primary involvement in a federally funded comparative project aimed at understanding the role of humanspecific 3D genome conformation and chromatin structure in human neuron development and neurodevelopmental disease.
The Knight Cardiovascular Institute (KCVI) is recognized as a top integrated center for cardiovascular clinical care translational research and professional training in all aspects of heart and vascular disease. Guided by a multidisciplinary approach researchers and clinicians drive a vibrant translational research program which focuses on delivering the latest knowledge and cutting edge care to patients. Specifically research at KCVI seeks to improve patient outcomes by achieving earlier diagnosis of disease more accurate monitoring of its progression and tailoring therapy to the molecular basis of disease.
Function/Duties of Position
The successful candidate will work closely with molecular biology laboratory staff and under the supervision of the Principal Investigator and a computational staff scientist.
Key responsibilities include executing and troubleshooting highthroughput (epi)genomic assayssuch as MicroC CUT&RUN RNAseq and ATACseqacross different species and cell types/tissues. The role will also involve analyzing nextgeneration sequencing data from these assays using established pipelines and opensource bioinformatics tools as well as integrating multiomic data to support research goals.
Additional responsibilities include contributing to manuscript writing presenting findings at scientific conferences and mentoring junior staff. In addition to the main project the postdoc will contribute to other ongoing lab projects with similar research scope offering a broad exposure to epigenomic research. Finally there is the possibility to contribute to the KCVI Epigenetics consortium which provides wet/dry services to investigators across different research areas (cardiovascular cancer aging etc..
Required Qualifications
- PhD degree in Genetics Molecular Biology Neuroscience Bioinformatics or closely related field
- Extensive wet lab experience with routine RNA and DNA assays as well as highthroughput (epi)genomic assay (e.g. MicroC CUT&RUN RNAseq ATAC seq)
- At least 2 years of experience executing bioinformatics analysis of nextgeneration sequencing data and familiarity with relevant tools and pipelines
- Strong understanding of molecular biology chromatin biology and gene regulation
- Proficient in using public bioinformatics tools (e.g. SAMtools BEDtools BWA) for analyzing highthroughput sequencing data
- Strong critical thinking problem solving and creativity in develoing resarch and analysis strategies
- Excellent oral and written communication skills with a strong track record of scientific publication
- Ability to work effectively both independently and as part of a multidisciplinary collaborative team
- Ability to prioritize tasks efficiently to meet project goals with a strong sense of selfmotivation and integrity
Preferred Qualifications
- Experience with crossspecies compartive analysis particularly in mammals
- Experience in singlecell assays cell culture and differentiation
- Proficiency in R coding languages and biostatistical methods
- Familiarity with data integration techniques
All are welcome
Employment Type
Full-Time
