Senior Scientist II or Principal Research Scientist I DNA-encoded Library
Senior Scientist II or Principal Research Scientist I DNA-encoded Library
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1 Vacancy
Job Description
The DNAencoded Library (DEL) platform group at AbbVie Headquarters in Lake County Illinois is seeking a highly talented and motivated scientist to enhance our DEL Chemistry development platform and DEL data analysis capabilities within our Small Molecule Therapeutics and Platform Technologies organization. The individual will work within our DEL Team and collaborate with crossfunctional groups including medicinal chemistry protein sciences biophysics and cheminformatics to drive AbbVie DEL platform developments. The successful candidate should possess strong communication and leadership skills and will be expected to contribute to various drug discovery projects across the therapeutic area portfolio of AbbVie interests.
Key Responsibilities:
- Be accountable for the design development and validation of DELs synthesis schemes with high structural diversity using robust chemistry.
- Supervise efforts to develop validate and implement innovative onDNA chemistry strategies. Provide technical supervision and expertise in standard and innovative synthetic methods as required.
- Interface with Medicinal Chemistry teams to enhance the DEL library portfolio hit expansion strategy and hit confirmation activities.
- Contribute to the development of computational tools and methodologies strengthen our DEL data analysis platform and support hit generation activities across AbbVie therapeutic area portfolio.
- Contribute to the direction and evolution of AbbVies DEL platform strategy.
Qualifications :
- BS MS or Ph.D. in Computational Chemistry Medicinal Chemistry or related discipline with typically 46 (PhD) 1012 (MS) or 1214 (BS) years of experience.
- Indepth knowledge and experience in all aspects of the DNAencoded Library platform (i.e. Library design DEL selections Next generation Sequencing NGS data analysis DEL hit confirmation strategies).
- Experience with modern cheminformatics tools computational tools data visualization and statistical analysis of large data sets is preferred.
- A proven track record of scientific publications in successfully applying DEL technology for hit generation against targets of pharmaceutical relevance.
- Demonstrable effective leadership skills.
- Demonstrated a high level of professionalism in working with internal and external collaborators to achieve specific outcomes.
- Excellent analytical and problemsolving skills as well as strong organizational skills.
- Excellent communication and influencing skills.
Position will be filled at level commensurate with extent of education experience and accomplishment. Senior Scientist II or Principal Research Scientist I.
Additional Information :
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
- The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location and we may ultimately pay more or less than the posted range. This range may be modified in the future.
- We offer a comprehensive package of benefits including paid time off (vacation holidays sick) medical/dental/vision insurance and 401(k) to eligible employees.
- This job is eligible to participate in our shortterm incentive programs.
- This job is eligible to participate in our longterm incentive programs
Note: No amount of pay is considered to be wages or compensation until such amount is earned vested and determinable. The amount and availability of any bonus commission incentive benefits or any other form of compensation and benefits that are allocable to a particular employee remains in the Companys sole and absolute discretion unless and until paid and may be modified at the Companys sole and absolute discretion consistent with applicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity driving innovation transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
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No
Employment Type :
Fulltime
Employment Type
Full-time
