Senior Scientist II Analytical RD
Senior Scientist II Analytical RD
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Job Description
AbbVie Analytical Research & Development (Analytical R&D) is a global analytical scientific organization responsible for all CMC analytical activities related to the development of AbbVies pharmaceutical scope includes AbbVies diverse pipeline of innovative small molecule and therapeutic biologic medicines and spans from the selection of Discovery candidate molecules to Late Stage are building a worldclass team of scientists and leaders who will drive the advancement of industryleading analytical capabilities and make meaningful contributions to advance AbbVies pipeline of innovative in AbbVie Analytical R&D provide unique opportunities to work with global and crossfunctional teams to drive exceptional science and innovative product development are looking for diverse candidates with strong scientific experience to join the AbbVie Analytical R&D team and can offer exciting and rewarding career opportunities for these candidates.
Position Description:
For the Senior Scientist II position we are seeking a highly motivated candidate who can conceive implement and execute novel scientific research and development. Generate new scientific proposals and lead these efforts. Act as a lead scientist in his/her area of expertise and critically evaluate relevant scientific and regulatory advances and integrate this knowledge into research and development programs.
This position will be within Analytical R&Ds Screening Lab which functions as a highthroughput method screening and development group that serves a diverse set of stakeholders and impacts all pipeline programs. The Screening Lab is seeking a Separations Scientist with experience in chromatographic method development for small molecules and biologics. An ideal candidate would have handson experience developing methods and troubleshooting difficult separations related challenges. Additionally He/she should possess an understanding of core discipline and support early phase development of New Chemical Entities (NCEs) and New Biologic Entities (NBEs) for both drug substance and drug product in preclinical and clinical programs.
An ideal candidate will have pharma related project lead experience and have a proven track record of developing novel approaches for method development and solutions for difficult separations. Additional experience with advanced CDS control process chromatography and automation as well as experience with emerging drug modalities (LNPs Peptides Oligos etc. is desirable. In this dynamic and fastpaced environment your expertise and insight will ensure that robust and reliable methods enable pipeline projects.
Responsibilities:
Support highthroughput platform screening capabilities for separationbased assays for smallmolecules and biologics (Chiral Achiral HILIC SFC 2DLC HIC IEX SEC etc.
Development of stability indicating methods using a variety of analytical separation (HPLC/UHPLC) and detection modes (UV MS CAD) for active pharmaceutical ingredients.
Employ chromatographic modeling software (Fusion Drylab Chromsword etc. for method development and robustness.
Apply analytical separation and detection modes for complex impurity profiling of pharmaceutical products to further the understanding of emerging cGMP manufacturing processes.
Perform assay qualifications to establish specificity sensitivity linear range precision robustness and accuracy of test methods.
Responsible for leading the analytical aspects of a project while working with other functional areas to advance projects through the development pipeline from preclinical to clinical candidates.
Utilize understanding of a range of analytical techniques to conduct research and development studies related to smallmolecule active pharmaceutical ingredients intermediates starting materials impurities along with preclinical to clinical formulations.
Communicate and collaborate with crossfunctional groups and departments.
Expected to evaluate novel technology approaches and build scientific profile both internally and externally in terms of pipeline contributions and scholarly achievements.
Contribute to writing of publications presentations and patents.
Qualifications :
Bachelors Masters or Ph.D. in Analytical Chemistry typically with a minimum of 12 (BS) 10 (MS) or 4 (Ph.D. years related industry experience.
Strong technical background in analytical chemistry excellent analytical problemsolving skills. Capable of independently developing and troubleshooting analytical methods.
Hands on experience with HPLC analysis and method development along with expertise and fundamental understanding of spectroscopic techniques.
Possesses a strong understanding of fundamental properties and theory of chromatography.
Experience in the use of computerized data handling systems.
Practical knowledge of organic structure functional groups chemistry and modern spectroscopic techniques as applied to smallmolecule analytical analysis.
Additional Information :
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location and we may ultimately pay more or less than the posted range. This range may be modified in the future.
We offer a comprehensive package of benefits including paid time off (vacation holidays sick) medical/dental/vision insurance and 401(k) to eligible employees.
This job is eligible to participate in our shortterm incentive programs.
This job is eligible to participate in our longterm incentive programs
Note: No amount of pay is considered to be wages or compensation until such amount is earned vested and determinable. The amount and availability of any bonus commission incentive benefits or any other form of compensation and benefits that are allocable to a particular employee remains in the Companys sole and absolute discretion unless and until paid and may be modified at the Companys sole and absolute discretion consistent with applicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity driving innovation transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
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No
Employment Type :
Fulltime
Employment Type
Full-time
