Scientist I Biology
Scientist I Biology
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Job Description
How will your role help us transform hope into reality
You will have the opportunity to contribute to early drug discovery programs as well as new target identification and validation to expand our drug discovery pipeline. This position offers the unique opportunity to directly impact a growing portfolio of targeted therapies in a fastpaced and innovative research environment. Your work will support Blueprint Medicines to bring nextgeneration treatments to benefit the right patients.
What will you do
- Lead from the bench to identify and validate novel targets within the oncology and/or immunology & inflammation space to grow Blueprints pipeline
- Independently conduct optimize and proactively troubleshoot cellular screening assays to support earlystage small molecule inhibitor or protein degrader drug discovery programs
- Proactively employ a breadth of cell and molecular biology techniques including gene targeting approaches and small molecule inhibition to dissect mechanism of action
- Design and execute experiments to evaluate target dependency phenotypic responses resistance mechanisms and drug combinations
- Process interpret and present data to crossfunctional team members to contextualize findings for the broader program
- Perform other responsibilities as assigned.
What minimum qualifications do we require
- BS with 8 years of experience in industry M.S. with 5 years of experience in industry or a PhD
What additional qualifications will make you a stronger candidate
- Highly skilled in standard laboratory techniques (e.g. mammalian cell culture) and a wide range of stateoftheart molecular and cellular biology techniques (e.g. RTqPCR flow cytometry immuneassays AlphaLISA InCell Western high content imaging (HCI) CRISPR gene editing etc)
- Ability to independently execute experiments to investigate the mechanism of action efficacy and safety of potential therapeutic targets using genetic and pharmacological approaches
- Familiarity with PK/PD/efficacy relationships and experience delivering PD readouts is a plus
- Ability to identify learn and adapt to new technologies as they become available
- Strong oral and written communication skills as well as excellent documentation and organizational skills
- Familiarity with standard software analytical tools (e.g. GraphPad Prism FlowJo Excel etc)
- Excellent time management skills and comfortable with multitasking to thrive in a fastpaced environment and meet deadlines
- Selfmotivated creative scientist with a strong cando attitude
- Strong problem solving and interpersonal skills to facilitate crossfunctional collaboration. A team player who listens effectively invites response and discussion
- Commitment to our Core Values: Patients First Thoughtfulness Urgency Trust Optimism
Why Blueprint
At Blueprint Medicines we achieve impactful results because of our global crew of compassionate innovators the Blue Crew. Through authentic relationships and our collective entrepreneurial spirit and action we are each empowered to take ownership and execute with strategic prioritization. We put trust in our people to break through norms and conventions using their individual strengths and insights which drives our success.
This is the place where the extraordinary becomes reality and you could be part of it.
Patients are waiting. Are you ready to make the leap
Equity Diversity Inclusion and Affirmative Action
At Blueprint Medicines we foster a culture of equity diversity and inclusion. A proud Equal Employment Opportunity and Affirmative Action employer we consider all qualified applicants without regard to race color sex gender identity or expression sexual orientation age religion national origin ancestry ethnicity disability veteran status genetic information or any other characteristic protected under applicable law. We are also an EVerify Employer. We will make reasonable accommodations absent undue hardship for qualified individuals with known disabilities. If you are an individual with a disability in need of an accommodation with the application or recruiting process please reach out to
For more information please see ourEEOAA Policy Statement the EVerify Participation Poster the Right to Work Poster and/or theEEO Know Your Rights Poster as well as ourPay Transparency Statement.
Blueprint Medicines is a global fully integrated biopharmaceutical company that invents lifechanging medicines. We seek to alleviate human suffering by solving important medical problems in two core focus areas: allergy/inflammation and oncology/hematology. Our approach begins by targeting the root causes of disease using deep scientific knowledge in our core focus areas and drug discovery expertise across multiple therapeutic modalities. We have a proven track record of success with two approved medicines including bringing our medicine to patients with systemic mastocytosis (SM) in the U.S. and Europe. Leveraging our established research development and commercial capability and infrastructure we now aim to significantly scale our impact by advancing a broad pipeline of programs ranging from early science to advanced clinical trials in mast cell diseases including SM and chronic urticaria breast cancer and other solid tumors.
#LIHybrid #LIAQ1
Employment Type
Full Time
