Genesis Therapeutics is a leader in AI guided rational drug design with the goal to address unmet medical needs in various indications including oncology and immunology.
Our San Diego lab is recruiting a Senior Research Associate/Scientist with experience in cellular and molecular immunology assay development cell biology and/or biochemistry with a proven interest in addressing inflammatory and autoimmune diseases.
More specifically we are seeking a candidate to execute SAR driving workflows while in parallel supporting mechanistic studies that advance multiple targets through preclinical development. This is a handson labbased position that requires close collaboration with colleagues across multiple functions.
Educational requirements consist of an advanced degree (MS or PhD) in a relevant field complemented by industry experience proportional to the level of education.
As an integral member of the team you will
Autonomously plan design and execute biochemical and cellbased experiments to support our I&I pipeline.
Maintain a handson approach while being an openminded flexible team player.
Analyze interpret and integrate complex datasets across multiple assay types.
Document data meticulously using ELN and stateoftheart analyses.
Stay at the forefront of latest research through literature review and critical evaluation of available data sources.
Ensure team progress and success through efficient communication with team members across the organization.
Your Qualifications are
A MSc or PhD degree in immunology molecular and cell biology biochemistry or a related field; with 5 or 3 years of relevant industry experience respectively.
A meticulous and detailoriented approach to experimental design with full commitment to scientific rigor and creative solutions.
A solid understanding of autoimmune and inflammatory mechanisms combined with a passion for preclinical drug research as evidenced by previous work experience.
Proven experience with highquality immunerelevant assays for compound profiling and MOA evaluations including but not limited to activation/proliferation assays cell differentiation coculture experiments cytokine analysis immune phenotyping and ex vivo culture and functional profiling of blood.
Solid expertise in RNA workflows from isolation/quantification/QC to downstream processing (qRTPCR RNAseq).
Fluency with MSD Luminex or other multiplex assays for bioanalyte quantification.
Robust experience with multicolor flow cytometry.
Experience in live cell imaging IF staining highcontent/highthroughput imaging and quantitative image analysis is a plus.
Critical understanding of assay development and validation for screening and compound progression purposes.
A highly organized workstyle with excellent written and oral communication skills.
Practical knowhow with industry standard equipment like automated plate readers liquid handlers and robotic platforms is highly valued.
Proficiency with data visualization and statistical analysis using contemporary software tools is a must.
What we offer
Participation in the growth of a pioneering company in AIdriven drug discovery.
Integration into a dynamic collaborative and forwardthinking environment.
Engagement with a multidisciplinary team to tackle challenging projects with a meaningful impact on patient lives
In addition we provide
Competitive Pay
Health Care Plans (including Medical Dental and Vision fully covered for the employees)
Our team has created the industrys most advanced molecular AI platform called GEMS (Genesis Exploration of Molecular Space) to accelerate and optimize small molecule drug discovery and to enable the discovery of novel firstinclass and bestinclass small molecule for challenging and/or undruggable targets.
The company has leveraged GEMS to build an internal pipeline with multiple programs against highvalue targets including datapoor and canonically undruggable targets where GEMS is uniquely advantaged. In addition Genesis has signed AIfocused platform collaborations with major pharmaceutical companies including most recently Incyte Corporation (Feb 2025 and Gilead Sciences (Sept 2024.
We raised a $200M series B in August 2023 and have raised over $300M in funding from top technology and biotech investors including Andreessen Horowitz Rock Springs Capital T. Rowe Price Fidelity Radical Ventures NVentures (NVIDIAs VC arm) BlackRock and Menlo Ventures.
Genesis is headquartered in Burlingame CA with a fully integrated laboratory in San Diego. We are proud to be an inclusive workplace and an Equal Opportunity Employer.
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