Laboratory Senior Scientist - AAV
Laboratory Senior Scientist - AAV
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Job Description
The Company
AAVantgarde is a clinicalstage international biotechnology company headquartered in Italy. We have developed two cuttingedge AAV vector platforms to overcome DNA cargo limitations targeting Usher syndrome type 1B and Stargardt disease. Founded by the renowned Professor Alberto Auricchio a pioneer in gene therapy our mission is to transform genetic medicine for patients with no current therapeutic options. Join us at AAVantgarde and be a part of our innovative journey to bring the next generation of genetic medicines to those in need.
The Role
Join our cuttingedge team as an AAV scientist where you will play a pivotal role in bioassay development from conception to the final transfer of method protocols to our external partners. If you have a proven track record of working with in vitro cell assays and molecular biological assays this opportunity is perfect for you. Reporting directly to the Head of Process and Analytical Development you will collaborate closely with the AAVantgarde CMC team members and CROs on the innovative development of AAV characterization methods.
In this exciting and rewarding role you will review relevant literature design experimental plans and execute analytical activities that support the characterization of our pipeline products. Your ability to clearly and concisely record and communicate results to all relevant internal and external stakeholders will be crucial. You will be responsible for the daytoday planning and timely of assigned projects including design development and writeup ensuring that the correct procedures are followed and the quality of work is upheld to the highest standard.
Working closely with crossfunctional groups such as process development QC preclinical development quality and regulatory affairs you will support the creation of regulatory filing sections related to analytical development and CMC. Additionally as a valuable member of the lab team you will ensure that laboratory facilities and equipment are well maintained and stocked for planned activities and contribute to the creation of COSHH and labrelated risk assessments. Your keen attention to detail in reporting hazards and incidents in a timely manner will help maintain a safe and productive work environment.
Step into this dynamic role and be part of a team that is at the forefront of AAV characterization making significant strides in the industry and contributing to groundbreaking advancements.
Skills and Experience Required
We are seeking a candidate who can manage their time independently demonstrating flexibility and adaptability to changing project priorities. The ideal candidate will have the ability to develop and communicate technical plans and outcomes effectively. They should excel at summarizing and communicating complex topics both verbally and in writing to internal and external stakeholders. A strong sense of ownership and accountability for analytical development activities is essential.
You will be a Ph.D. (or MSc with equivalent experience) in cellular biology virology chemical engineering Molecular Biology Biology Genetics Analytical/Organic engineering or a related natural science discipline is required. The candidate should have over 5 years of experience in developing qualifying validating and tech transferring biological assays. A proven track record in applying DoE and QbD development principles in method development is highly desirable. Handson experience in AAV gene therapy analytical development and assay including working with various relevant cell lines (HEK293 HeLa ARPE19 etc. is crucial. Knowledge in GxP compliance data integrity and tech transfer activities to ensure a smooth transition from analytical development to QC testing is also required.
Whats in it for You
At AAVantgarde we believe in creating an environment where our employees can thrive. Our central London office offers a prime location with topnotch facilities. As a rapidly growing biotech with recent funding there are ample opportunities for career advancement and as we grow so can you. We offer a generous salary bonus pension health insurance through Vitality and income protection ensuring you have the support and resources you need to succeed. Join us and be part of an exciting innovative journey in the world of biotechnology.
Equal Opportunities
At AAVantgarde we are committed to fostering a welcoming collaborative and inclusive environment. We believe in providing equal opportunities for all and do not discriminate on the basis of race colour religion sex sexual orientation gender identity national origin disability or any other legally protected characteristics. All applicants will receive equal consideration for employment.
Recruitment Policy
AAVantgardes HR team leads all recruitment activities for AAVantgarde globally. AAVantgarde will not recognise any notional ownership recruitment companies claim to hold over candidates they present directly to hiring managers without the AAVantgarde HR teams consent nor any fees the recruitment company may feel are due as a result of this. Unsolicited resumes sent to AAVantgarde from recruiters do not constitute any type of relationship between the recruiter and AAVantgarde and do not obligate AAVantgarde to pay fees should we hire from those resumes. We ask that external recruiters and/or agencies not contact or present candidates directly to our hiring managers or employees. If you are interested in becoming a recruitment partner please email the HR team at
Required Experience:
Senior IC
Employment Type
Full-Time
