Senior Medical Director Translational Medicine Neurology
Senior Medical Director Translational Medicine Neurology
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Job Description
Senior Medical Director Translational Medicine Neurology
Introduction
The Medical Director of Translational Medicine will play a critical role in bridging the gap between preclinical research and clinical application.
This position involves leading efforts to develop and implement strategies that ensure the effective transition of therapies from the lab to clinical trials.
This individual will lead translational aspects of neurologic clinical studies collaborating with crossfunctional teams to support translational and experimental medicine. The role will focus on neurologic rare diseases across the Neurology Therapeutic Area (TA) and Genomic Medicine Development Unit at Alexion.
The ideal candidate will have a strong background in translational medicine with a focus on neurology rare diseases and preference with experience in rare diseases.
What You Will Do
Create and execute translational science and experimental medicine plans
Develop in collaboration with other members of the cross functional team clinical and scientific aspects of translational studies from preclinical through ProofofConcept studies supporting:
Human target validation
Candidate indication selection
Preliminary clinical plan development
Collaborate with early clinical development leaders within the DRS Development organization to support the transition from Research to the DRS Development organization in preparation for IND
Partner with Translational Research team to drive connectivity between the Research and Development organizations
Support crossfunctional teams on INDenabling studies
Support the design of early clinical trials through ProofofConcept including experimental medicine studies
Through collaboration design and execute translational plans (including clinical biomarkers supporting target engagement MoA and proof of biology across various modalities) to support clinical development programs.
Develop and implement patient enrichment strategies to support the core aspects of the program
Prepare and review study protocols clinical study reports and translational medicine sections of plans abstracts and technical reports
Serve as a scientific and medical expert in translational medicine providing guidance and insights to internal teams and external partners.
Collaborate with crossfunctional teams during the design and reporting of earlystage clinical trials to ensure that biomarker and other translational data is available at the time of clinical trial result readout.
Lead or participate in crossfunctional working groups and engage in external interactions with academic institutions and scientific experts.
Present results and updates of projects at department project corporate and scientific meetings.
Stay updated on the latest advancements in neurologic translational medicine and rare disease research incorporating new knowledge into ongoing projects.
Who You Are
Medical Degree (MD) with board certification/board eligible in Neurology is Required; In addition PhD or strong research experience is preferred.
Minimum of 3 years in early clinical development translational medicine or translational research in an industry setting; exceptional individuals with academic trial/research experience will be considered.
Indepth knowledge in a core neurology specialty area with broad understanding of the wider scope of neurology diseases is strongly preferred.
Proven competence in clinical therapeutics drug development and early clinical development.
Thorough understanding of FDA and ethical guidelines relevant to the pharmaceutical industry.
Excellent communication skills and ability to interact professionally with individuals at all levels of experience and across worldwide cultures.
Conscientious enthusiastic team player with excellent collaboration and teamwork abilities.
Strong analytical and evaluative skills.
Working at Alexion
Were inspired to think differently to create better outcomes. By creating an unparalleled employee experience our organization is equipped to adapt and enrich employees with a productive engaging and enjoyable work experience while accelerating worldclass leadership and innovation capabilities that can deliver on our mission. Each of us is accountable for delivering innovative medicines and supportive technology with integrity so we can truly understand and better the lives of people affected by rare diseases. Together we can transform lives every day.
The Highest Standards
By operating with the highest standards of ethics and integrity we aspire to live up to the expectations of patients physicians and ourselves and to earn trust in our communities.
Diversity
We encourage diversity of backgrounds and ideas. We genuinely care for and respect each other working together as a highperforming team to deliver extraordinary results while embracing different perspectives.
Dedication
The dedication and passion of our employees enable us to stay focused on what matters most. We push ourselves to achieve the highest level of medical innovation and to redefine what it means to live with a rare disease.
This role has an expectation of working in the office 3 days a week. When we put unexpected teams in the same room we unleash bold thinking with the power to inspire lifechanging medicines. Inperson working give us the platform we need to connect work at pace and challenge perceptions. Thats why we work on average a minimum of three days per week from the office. But that doesnt mean were not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.
AstraZeneca requires all US employees to be fully vaccinated for COVID19 but will consider requests for reasonable accommodations as required by applicable law.
AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds with as wide a range of perspectives as possible and harnessing industryleading skills. We believe that the more inclusive we are the better our work will be. We welcome and consider applications to join our team from all qualified candidates regardless of their characteristics. We comply with all applicable laws and regulations on nondiscrimination in employment (and recruitment) as well as work authorization and employment eligibility verification requirements.
Date Posted
08Apr2025Closing Date
21Apr2025Alexion is proud to be an Equal Employment Opportunity and Affirmative Action employer. We are committed to fostering a culture of belonging where every single person can belong because of their uniqueness. The Company will not make decisions about employment training compensation promotion and other terms and conditions of employment based on race color religion creed or lack thereof sex sexual orientation age ancestry national origin ethnicity citizenship status marital status pregnancy (including childbirth breastfeeding or related medical conditions) parental status (including adoption or surrogacy) military status protected veteran status disability medical condition gender identity or expression genetic information mental illness or other characteristics protected by law. Alexion provides reasonable accommodations to meet the needs of candidates and employees. To begin an interactive dialogue with Alexion regarding an accommodation please contact Alexion participates in EVerify.Required Experience:
Director
Employment Type
Full-Time
