Expert GPCR Cellular Assays GN
Expert GPCR Cellular Assays GN
Posted on :
11-04-2025
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1 Vacancy
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Job Description
Your mission
- Contribute to multidisciplinary and challenging research projects in the field of drug discovery.
- Provide expert knowledge in GPCR biology focusing on GPCR/Gprotein interactions and ligand pharmacology.
- Independently design execute and interpret cellular functional assays for profiling and classifying ligands based on their mode of stimulation.
- Develop and apply fluorescence and luminescence assays with continuous kinetic readout on FLIPR or FDSS workstations.
- Perform ligand screening in HTS mode and ligand profiling experiments.
- Utilize cell culture techniques and select relevant cell lines.
- Ensure compliance with industry standards for screening profiling and characterization of ligandGPCR binding.
- Maintain thorough documentation of work according to internal guidelines and customer requirements using a laboratory management system (LIMS).
Your profile
- Ph.D. in cell biology pharmacology biochemistry or a related field with a strong focus on membrane protein signaling.
- At least 3 years of experience in a drug discovery environment covering the process from screening to lead identification.
- Deep understanding of GPCR pharmacology and Gprotein interactions.
- Handson experience with FLIPR or FDSS workstations
- Proven expertise in other fluorescence and luminescencebased GPCR assay technologies such as TRFRET FRET nanoBRET.
- Strong analytical and problemsolving skills with a high level of accuracy and attention to detail.
- Ability to work independently and in interdisciplinary teams across different projects.
Why us
- An innovative professional field in an exciting industry
- An inspiring working atmosphere as fertile ground for your further development
- A comprehensive induction that prepares you optimally for your area of responsibility
- Multicultural teams and an open corporate culture
- A salary in line with the market
Contact Details
Proteros biostructures GmbH
People Team
Bunsenstr.7a 82152 Martinsried
About us
Proteros is a privately held earlystage services provider in structurebased drug discovery with a cuttingedge discovery engine tailored to unlock even the most technically challenging targets. Proteros work is built on scientific excellence and supports its clients to reach the right results and accelerate their overall research timelines. Proteros supports most of the worlds 20 largest pharma companies and more than 250 pharmaceutical and biotech partners in the US Europe and Japan.
Employment Type
Full-Time
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