Co-op Student Bioinformatics

The Cystic Fibrosis Foundation is a leading healthcare nonprofit organization like no other. For decades we have been taking major steps and pioneering new ways to advance the mission to find a cure for cystic fibrosis and to provide all people with CF the opportunity to lead long fulfilling lives by funding research and drug development partnering with the CF community and advancing highquality specialized care.

We are the global leader in the search for a cure for cystic fibrosis and nearly every CF drug and therapy available today was made possible because of CF Foundation support. We did this not only for the close to 40000 people living in the U.S. with CF and the estimated 105000 people worldwide but for the people with CF and families who have worked tirelessly to support the mission.

These achievements have required dedication and unwavering commitment from a talented team of CF Foundation employees. We promote an environment that attracts and retains a diverse group of talented people who are passionate about eradicating this disease . Join us and you will join an amazing team devoted to our community and our mission.

Position Description

The Cystic Fibrosis Foundation (CF Foundation) and its employees embrace their commitment to its core values. These core values are the pillars on which the CF Foundation stand and will continue to sustain us as we move forward.

• Keep sight of what really matters: Our decisions are based on what is best for people with cystic fibrosis and their families.

• Aspire for excellence in all we do: We take pride in our work. We are committed to continuous learning and improvement.

• Stronger together: We collaborate and work together so that we can learn more and achieve more.

• Innovate with courage: We embrace challenges. We reach beyond boundaries in pursuit of our vision.

• Care about our people: We deeply care about each other and all who support our shared mission. We listen with respect. We support one another.

We are a nonprofit donorsupported organization that has raised and invested billions of dollars to help develop cystic fibrosis therapies that have changed the lives of people with this disease. Nearly every CF medicine available today was made possible because of Foundation support.

CFF LAB:

The Cystic Fibrosis Foundations oneofakind CF research facility located in Lexington MA bridges the gap between discoveries made at academic institutions and the development of new therapies by the biotech and pharmaceutical industry. The Labs mission is to facilitate and expedite the discovery of that could correct or improve the function of the defective cystic fibrosis transmembrane conductance regulator (CFTR) protein. Since it first opened in 2012 the vision for the lab has evolved together with the science and with the transformative CF treatments becoming available; the current focus is on developing novel CF treatments especially for those with rare and nonsense genetic variants who cannot be treated with CFTR modulators. Additionally the lab is concentrating research on enabling genetic therapies that would ultimately offer the best hope for a cure for CF for everyone regardless of the CFcausing genetic variant.

COOP PROGRAM SUMMARY:

This research experience will focus on learning how scientific discovery data can be translated to treatment of disease. Students will join the Bioinformatics team in the Laboratory and carry out an independent research project and may assist with ongoing projects. The purpose of the coop term will be to: 1 immerse students in areas of biomedical science not readily accessible on undergraduate campuses 2 provide an opportunity for firsthand knowledge of how new data are obtained and interpreted 3 experience the process of research as a creative intellectual activity and gain a more realistic view of the opportunities and demands of a professional research career 4 allow students to gain an indepth understanding of cystic fibrosis (CF) and the rapidly advancing therapeutic landscape for CF.

POSITION SUMMARY:

Works under supervision on projects conducted within the Bioinformatics team. Will gain handson experience in a variety of basic and stateoftheart software and data tools in order to work closely with the Bioinformatics team members on computational capabilities databases software tools and solutions for organizing analyzing and integrating internal and/or public experimental data in particular Next Generation Sequencing (NGS) and genetic variant data. Will learn to analyze data and be able to present findings to supervisor. Can expect to prepare and present a 15minute PowerPoint presentation in an internal group setting.

ESSENTIAL DUTIES AND RESPONSIBILITIES:

• Conduct computational analysis of experimental data.

• Troubleshoot and understand experimental activities.

• Develop and maintain computational solutions scripts software tools and computational pipelines.

• Perform analysis of lab results for discussion with supervisor.

• Maintain detailed records of the work conducted (electronic lab notebook).

• Collate results in preparation for internal meetings.

KNOWLEDGE SKILLS AND ABILITIES REQUIRED:

• Active student in a degreed college or university Bioinformatics/Life Sciences program.

• Excellent attention to detail.

• Excellent communication collaboration problem solving skills.

• Detailoriented and capable of multitasking in a dynamic team.

• Familiarity with computer programming ability to write short programs or scripts independently.

• Coursework in computer science/bioinformatics and in biological disciplines (genetics molecular biology).

REPORTING RELATIONSHIPS:

• Reports to the Director II Facilities and Operations.

WORKING CONDITIONS:

• Commute to lab every workday. Must have access to reliable transportation.

• Supervised work at the Lab.

• Sitting bending reaching and walking.

The above is intended to describe the general content of and requirements for the performance of this job. It is not to be construed as an exhaustive statement of essential functions responsibilities or requirements.

COMPENSATION:

This paid internship opportunity offers a pay rate of $25.00 per hour.

This position will be posted for a minimum of 5 days or until the position is filled. Applications will be accepted on an ongoing basis so candidates are encouraged to apply promptly if interested.

Total Rewards: The CF Foundation is committed to offering competitive compensation (base pay and incentive) benefits and professional development opportunities that maximize our ability to recruit retain reward and motivate a highly qualified and diverse workforce. Our comprehensive benefits package includes medical dental and vision coverage; a holistic wellbeing program; health savings and flexible spending accounts; employerprovided life and disability insurance; retirement savings benefits; and a variety of worklife benefits to support employees and their family members. In addition the CF Foundation offers fulltime employees 20 days of vacation and 10 days of sick per year prorated based on hire date as well as 14 paid holidays 2 personal days and a variety of generous leave benefits. Visit ourWhy Work at the Cystic Fibrosis Foundationpage to learn more.

The CF Foundation is an equal opportunity employer that is committed to being an employer of choice not just a good place to work but a great and inclusive place to work. We strive to recruit and maintain a diverse workforce. Qualified applicants will receive consideration for employment without regard to race physical or mental disability color religious creed ancestry national origin religion age sex pregnancy marital status genetic information or testing gender identity and expression sexual orientation or status as a Vietnamera or special disabled veteran or any characteristic protected by law.

Reasonable Accommodations: The CF Foundation is committed to providing reasonable accommodations for qualified individuals with disabilities in our job application procedures. If you need assistance or would like to request an accommodation due to a disability please contact us at