Demonstrated independence in experimental design data analysis and interpretation
Ability to work in a high paced team environment meet deadlines & prioritize work on multiple projects
Excellent analytical skills attention to detail and demonstrated independent decision making
Excellent verbal and written communication skills
Proficiency in Word PowerPoint Excel and Internet based applications is required.
Ability to handle human blood and blood products perform sterile tissue culture in accordance with established standard operating procedures (SOP) and guidelines.
Some experience in flow cytometry and ELISA is desired.
B.S. or M.Sc. in molecular biology or related field.
- 3 or more years of directly relevant experience. 1 years of protein expression and purification experience required.
- Expertise in purification techniques including affinity sizeexclusion charge based chromatography
- Preferred experience with AKTA chromatography system.
- Preferred Experience with small scale liquid handling systems (Preferred)
- Experience with molecular biology techniques
The Cobbold laboratory within the Center for Cancer Immunology at the MGH Cancer Center is seeking a highly motivated and wellorganized individual for a fulltime Research Technologist position.
Dr. Cobbolds laboratory focuses on tumor antigens and antibodybased targeting of cancer by mobilizing the immune response. The candidate will optimize develop and execute protein expression and purification to support the biotherapeutics group. Attractive candidates will have a demonstrated track record of high quality and timely data generation excellent communication skills and should be comfortable working at the bench in a fastpaced and multitasked interdisciplinary teamoriented environment.
PRINCIPAL DUTIES AND RESPONSIBILITIES:
Implement and optimize a broad range of protein expression platforms purification techniques and characterization methods to support preclinical development.
Undertake molecular biology cloning small scale expression and purification liquid handling automation and AKTA chromatography system.
Design perform and troubleshoot experiments with only general guidance from the laboratory director. This includes collection of and accurate recording of procedures and results maintenance of databases used in the lab ordering necessary reagents to conduct experiments and participation in joint upkeep of the lab.
Prepare written reports on status of research determination of technical procedures sequence of operations including statistical and graphic summaries of findings and possible conclusions. Collaborates with laboratory director in writing and editing material for publication and may appear as principal or secondary author on publications.
Will assist in hiring and training lower level technical personnel.