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The Position

A healthier future. Its what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. Thats what makes us Roche.

Within Roches Pharma Research and Early Development (pRED) Neuroscience & Rare Diseases (NRD) we are committed to realizing the vision of the Roche One Pharma Strategy in Neurology to preserve and restore what makes people who they are. Our research and early development activities center around large and rare indications within four major therapeutic network areas: Dementias Multiple Sclerosis Movement Disorders and Neuromuscular & Neurodevelopmental Disorders. With strengths across diverse disciplines Roche is uniquely positioned to lead in transforming science to medicines for patients with disorders of the nervous system.

The Opportunity:

Roche is seeking a Therapeutic Area Leader for Dementias. Reporting to the SVP and Global Head of Neuroscience & Rare Diseases (NRD) at Roche pRED the Therapeutic Area Leader will work closely and seamlessly with all departments within NRD including Research Early Development Biomarkers Operations and Portfolio Development as well as with other organizations across pRED and Roche. The Therapeutic Area Leader will provide strategic and functional leadership of the crossdepartmental network. Major responsibilities and accountabilities of the Therapeutic Area Leader will include:

• Articulate and implement the strategy within the therapeutic area network

• Establish an intellectual home for the Dementia network of pRED aimed at ensuring the successful delivery of the portfolio in the therapeutic area from target assessment to completion of early clinical development

• Foster interdepartmental collaborative efforts on the portfolio assessment and selection of external Partnering opportunities

• Critical advisory role for portfolio project teams

• Coordination of initiatives and efforts in the therapeutic area across Roche

• Anticipate new trends in research technologies and programs to help promote rigorous
  exploration of new targets and enhance the translatability of molecules from preclinical to
  clinical studies

• The Therapeutic Area Leader will also serve as a member of the NRD Leadership Team
  (NLT) as well as the NRD Board

• Represent NRD both internally and externally at conferences and international meetings as
  well as on joint advisory and governance bodies with external partners

In addition to providing leadership for the therapeutic area the Therapeutic Area Leader will have the versatility to serve in embedded fashion in one of the NRD departments in a key capacity.

Who you are:

You will bring a PhD or MD/PhD with expertise in Dementia and specifically experience in Alzheimers and at least 10 years of R&D experience including senior leadership in the pharmaceutical industry. Alternatively you will be a renowned leader in Dementia within academia with a record of accomplishments in basic or clinical neuroscience and at least 10 years of experience as an independent investigator subsequent to postdoctoral training. Ideally you will also have a strong track record of successfully translating molecules from discovery into the clinical setting as well as an understanding of regulatory payer and commercial issues in the pharmaceutical industry.

In addition you will have demonstrated competencies in the following areas:

• Scientific accomplishments: Significant scientific accomplishments insights and acumen. Strong record of success in research and clinical development efforts will be important as well as evidence of leadership in neuroscience

• Collaborative leadership: Inspires diverse individuals to work together persuades others to pursue innovative ideas and can work with a large number of partners across the organization with the aim of improving performance and meeting goals. Proven track record as a scientific negotiator with the ability to find winwin scenarios

• Strategic leadership: Articulate strategic frameworks to inform operational delivery of the portfolio in Dementia. Ability to contribute strategic insights to prioritization and decisionmaking. Articulate longterm opportunities and threats in the therapeutic area evaluate options and take proactive steps to address them.

Who we are

A healthier future drives us to innovate. Together more than 100000 employees across the globe are dedicated to advance science ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities foster creativity and keep our ambitions high so we can deliver lifechanging healthcare solutions that make a global impact.

Lets build a healthier future together.

Basel is the headquarters of the Roche Group and one of its most important centres of pharmaceutical research. Over 10700 employees from over 100 countries come together at our Basel/Kaiseraugst site which is one of Roches largest sites. Read more.

Besides extensive development and training opportunities we offer flexible working options 18 weeks of maternity leave and 10 weeks of gender independent partnership leave. Our employees also benefit from multiple services on site such as childcare facilities medical services restaurants and cafeterias as well as various employee events.