Senior Director Precision Medicine Therapeutic Area Lead - CardiometabolicGeneral Medicine

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Job Description

Join Amgens Mission of Serving Patients

At Amgen if you feel like youre part of something bigger its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do.

Since 1980 weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology Inflammation General Medicine and Rare Disease we reach millions of patients each year. As a member of the Amgen team youll help make a lasting impact on the lives of patients as we research manufacture and deliver innovative medicines to help people live longer fuller happier lives.

Our awardwinning culture is collaborative innovative and science based. If you have a passion for challenges and the opportunities that lay within them youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Senior Director Precision Medicine Therapeutic Area Lead Cardio/Metabolic

What you will do

Lets do this. Lets change the world. In this vital role you will act in conjunction with the General Medicine/Cardiometabolic Therapeutic Area Head to drive the development and of Precision Medicine objectives. As the Precision Medicine Therapeutic Area Lead you will guide the strategic vision and integration of translational and precision medicine strategies across asset and aboveasset programs throughout the product lifecycle.

You will:

• Lead crossfunctional teams to develop and implement phaseappropriate integrated biomarker and human data strategies to support translational pharmacology and inform patient stratification/selection.
• Develop lead and serve as the strategic integrator of diverse stakeholder input and multiple lines of scientific and clinical evidence to create precision medicine strategies at the asset and indication level.
• Shape the strategic vision to enhance the value of the portfolio through clinical biomarker target identification indication selection early demonstration of biological activity and patient stratificationincluding reverse translational insights.
• Lead all aspects of precision medicine approaches by incorporating mechanistic insights and multiomics data (e.g. genomic proteomic) into actionable clinical development strategies.
• Serve as the primary translational bridge between Research and Development advising on clinical proofofconcept target engagement dose selection and reverse translational strategies for assets in the clinic.
• Drive innovation to shape therapeutic area strategy including disease endotyping indication prioritization and combination approaches while also supporting regulatory and access evidence generation plans.
• Engage crossfunctionally to evaluate propose and present strategies for data sourcing collaborative partnerships and funding needs to the appropriate Commercialization Governance Forums.
• Build and maintain strong external collaborations with academic institutions industry partners and key opinion leaders to accelerate precision medicine innovation in cardiometabolic diseases.

What we expect of you

We are all different yet we all use our unique contributions to serve patients. The dynamic professional we seek is a strategic thinker and scientific leader with a passion for patientcentered drug development and precision medicine.

Basic Qualifications:

Doctorate degree and 5 years of relevant industry or academic translational research experience

Or

Masters degree and 8 years of relevant experience

OR

Bachelors degree and 10 years of relevant experience

Preferred Qualifications:

• MD PhD or MD/PhD with 8 years of pharmaceutical/biotech experience focused on clinical development and translational science in cardio/metabolic diseases
• Deep expertise in translational research clinical biomarkers and precision medicine approaches in cardiovascular metabolic or renal disease
• Scientific and analytical expertise in integrating multiple data sources e.g. omic clinical Real world evidence (RWE) to inform precision medicine approaches
• Demonstrated ability to develop and implement successful biomarker strategies across early and latestage clinical programs
• Experience working in matrixed crossfunctional teams and leading external partnerships
• Knowledge of clinical trial design GCP and regulatory pathways for biomarker and diagnostic development
• Exceptional communication skills and ability to influence internal collaborators and external partners
• Demonstrated success in mentoring and growing scientific teams

What you can expect of us

As we work to develop treatments that take care of others we also work to care for your professional and personal growth and wellbeing. From our competitive benefits to our collaborative culture well support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to relevant skills experience and qualifications.

In addition to the base salary Amgen offers a Total Rewards Plan based on eligibility comprising of health and welfare plans for staff and eligible dependents financial plans with opportunities to save towards retirement or other goals work/life balance and career development opportunities that may include:

• A comprehensive employee benefits package including a Retirement and Savings Plan with generous company contributions group medical dental and vision coverage life and disability insurance and flexible spending accounts
• A discretionary annual bonus program or for field sales representatives a salesbased incentive plan
• Stockbased longterm incentives
• Awardwinning timeoff plans
• Flexible work models including remote and hybrid work arrangements where possible

Apply now and make a lasting impact with the Amgen team.

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Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

As an organization dedicated to improving the quality of life for people around the world Amgen fosters an inclusive environment of diverse ethical committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race color religion sex sexual orientation gender identity national origin protected veteran status disability status or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process to perform essential job functions and to receive other benefits and privileges of employment. Please contact us to request accommodation.

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