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The Position

A healthier future. Its what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. Thats what makes us Roche.

The Position

The Institute of Human Biology (IHB) at Roche in Basel Switzerland is offering an internship position for a motivated researcher to join our team. This internship provides an exciting opportunity to learn and contribute to IHBs cuttingedge research using advanced 3D human organoid systems to model and explore human health and disease. Your research will involve the development of new tools for CRISPR screening in complex intestinal organoid models involving cocultures of epithelial and immune cells. These experiments aim at dissecting the roles of genetic drivers of intestinal transformation and their role in modulating crosstalk with tissueresident immune cells.

Your Profile

You are currently enrolled in a university M.Sc. program in relevant subjects such as immunology molecular biology bioengineering or a related field or you have completed your degree in the respective subjects within the past 12 months.

• You have experience in primary cell culture. Prior experience with the culture of complex human model systems such as organoids or primary immune cells is highly desirable.

• Prior experience with CRISPR tools flow cytometry microscopy singlecell omics and/or next generation sequencing (NGS) is highly desirable.

• You are able to plan and perform experiments independently including their thorough interpretation and efficient documentation.

• You are fluent in English and highly curious about science and are able to derive novel approaches and ideas from published literature.

• You want to work in a highly collaborative environment where scientific exchange is highly valued.

Your impact

• Build workflows for genetic screening to dissect epithelialimmune interactions in complex human organoid models

• Study the role of specific genetic alterations (singlenucleotide variants large chromosomal deletions) in intestinal tumorigenesis

• Interpret experimental data and report these in presentations and a written report to colleagues

Your application

Your complete application should include the following documents:

• A CV and a Motivation Letter (including the name of 2 references).

• A certificate of enrollment (if you are currently studying).

• A 1minute video where you introduce yourself

• For NonEU/EFTA citizens: Due to regulations you must provide a letter from your university stating that an internship is mandatory for your studies and specifying the required length of the internship. Please upload this letter along with your enrollment certificate CV and motivation letter.

Employment: 100

Start date: As soon as possible; flexible

Duration: 912 months

Location: Basel Switzerland

If you are proud of contributing and feel you have the dedication to teamwork and innovation that we are seeking then Roche is the organization for you. Every role at Roche plays a part in making a difference to patients lives.

If you want to work in a passionate team make your mark & improve lives apply now.

Who we are

A healthier future drives us to innovate. Together more than 100000 employees across the globe are dedicated to advance science ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities foster creativity and keep our ambitions high so we can deliver lifechanging healthcare solutions that make a global impact.

Lets build a healthier future together.

Basel is the headquarters of the Roche Group and one of its most important centres of pharmaceutical research. Over 10700 employees from over 100 countries come together at our Basel/Kaiseraugst site which is one of Roches largest sites. Read more.

Besides extensive development and training opportunities we offer flexible working options 18 weeks of maternity leave and 10 weeks of gender independent partnership leave. Our employees also benefit from multiple services on site such as childcare facilities medical services restaurants and cafeterias as well as various employee events.