2025 Co-Op Protein Design

The Role
Moderna is seeking a highly motivated Coop to join the Protein Design team at our Cambridge MA site. In this role you will support protein production for the Infectious Diseases and Therapeutic Areas contributing to the development of different programs. Your responsibilities will include expressing purifying and characterizing recombinant proteins using bacterial and mammalian cell culture systems applying chromatographic techniques for protein purification and performing biochemical analyses to assess protein quality. Additionally you will have the opportunity to explore and optimize expression and purification strategies for challenging targets. This role requires strong attention to detail adaptability and the ability to work in a fastpaced environment ensuring the timely delivery of highquality recombinant proteins to support research efforts.

All candidates must be available for the full duration of the program. This program will run from Monday July 21st and end Friday December 12th 2025.

Heres What Youll Do

• Express recombinant proteins primarily in Escherichia coli and mammalian cells with occasional use of other hosts.

• Purify proteins using chromatographybased methods including affinity ion exchange and sizeexclusion chromatography leveraging FPLC systems for semiautomated workflows.

• Optimize expression and purification conditions to enhance yield and quality.

• Characterize proteins using SDSPAGE Western blot thermal shift assays activity assays and Octet binding assays.

• Communicate project objectives timelines progress and results effectively across crossfunctional teams.

• Analyze interpret and present experimental findings in group project and department meetings.

Heres What Youll Need (Basic Qualifications)

• Bachelors degree in Biochemistry Biology Molecular biology or related discipline or Masters degree in Biochemistry Biology Molecular biology or related discipline

• Coop/intern industry experience in protein biochemistry laboratory preferred

Heres What Youll Bring to the Table (Preferred Qualifications)

• Experience with bacterial or mammalian cell culture techniques

• Experience using standard methods to express and purify recombinant proteins

• Experience in biochemical characterization of proteins (e.g. SDSPAGE analytical SEC western blot thermal melt)

• Ability to participate in multiple collaborative projects in a crossfunctional team environment

• Strong quantitative analysis skills

• Excellent written and oral communication

• A desire to make an impact as part of a highgrowth transformational company that is Bold Relentless Curious and Collaborative.

At Moderna we believe that when you feel your best you can do your best work. Thats why our US benefits and global wellbeing resources are designed to support youat work at home and everywhere in between.

• Free premium access to meditation and mindfulness classes
• Subsidized commuter benefits
• Generous paid time off including:
  Vacation sick time and holidays
  Volunteer time to participate within your community
  Discretionary yearend shutdown
• Locationspecific perks and extras!

About Moderna

Since our founding in 2010 we have aspired to build the leading mRNA technology platform the infrastructure to reimagine how medicines are created and delivered and a worldclass team. We believe in giving our people a platform to change medicine and an opportunity to change the world.

By living our mission values and mindsets every day our people are the driving force behind our scientific progress and our culture. Together we are creating a culture of belonging and building an organization that cares deeply for our patients our employees the environment and our communities.

We are proud to have been recognized as a Science Magazine Top Biopharma Employer a Fast Company Best Workplace for Innovators and a Great Place to Work in the U.S.

As we build our company we have always believed an inperson culture is critical to our success. Moderna champions the significant benefits of inoffice collaboration by embracing a 70/30 work model. This 70 inoffice structure helps to foster a culture rich in innovation teamwork and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn contribute and make a meaningful impact.

If you want to make a difference and join a team that is changing the future of medicine we invite you to visit modernatx/careers to learn more about our current opportunities.

Moderna is a smokefree alcoholfree and drugfree work environment.

Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day please apply!

Moderna is committed to equal employment opportunity and nondiscrimination for all employees and qualified applicants without regard to a persons race color sex gender identity or expression age religion national origin ancestry or citizenship ethnicity disability military or protected veteran status genetic information sexual orientation marital or familial status or any other personal characteristic protected under applicable law.

Moderna is an EVerify Employer in the United States. We consider qualified applicants regardless of criminal histories consistent with legal requirements.

Were focused on attracting retaining developing and advancing our employees. By cultivating a workplace that values diverse experiences backgrounds and ideas we create an environment where every employee can contribute their best.

Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations team at . (EEO Employer)