Senior Principal Scientist Obesity andor Cardiometabolic Diseases
Senior Principal Scientist Obesity andor Cardiometabolic Diseases
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1 Vacancy
Job Description
About Us
Valo Health is a technology company that is integrating humancentric data and AIpowered technology to accelerate the creation of lifechanging for more patients faster. Valo was created with the belief that the drug discovery and development process can and should be faster and less expensive with a much higher probability of success. We are using models early to fail less often executing clinical trials to add valuation to the company and generating fitforpurpose data to feed back into Valos Opal Computational Platform as we reinvent drug discovery and development from the ground up. Disease doesnt wait so neither can we.
We are a multidisciplinary team of experts in science technology and pharmaceuticals united in our mission to achieve better for patients faster. Valo is committed to hiring diverse talent prioritizing growth and development fostering an inclusive environment and creating opportunities to bring together a group of different experiences backgrounds and voices to work together. We achieve the widestranging impact when we leverage our broad backgrounds and perspectivestoaccelerate a new frontier in health. Valo seeks to become the catalyst for the pharmaceutical industry and drive the digital transformation of the industry. Are you ready to join us
About the Role...
Valois looking for a Senior Principal Scientists to play a pivotal role in evaluating and prioritizing drug targets for obesity type 2 diabetes and cardiovascular diseases identified using Valos human centric Opal computational platform. This position requires deep expertise in the biology of obesity or cardiovascular diseases a background in drug discovery and a passion for translating human data insights to develop new therapies for complex diseases. You will be responsible for reviewing human evidence discovered using Valos computational platform and generating expertdriven insights contributing to the prioritization of candidate targets. As target champion and field expert you will be responsible for delivering target data packages and presenting evidence and rationale for prioritization to internal and external stakeholders. You will contribute to the continuous improvement of the target evaluation and prioritization process by innovating and closely collaborating with subject matter experts computational scientists and engineers. You will participate as subject matter expert in the development of research hypotheses that will shape Valos target discovery strategy.
What Youll Do
Your primary areas of responsibility will be:
- Comprehensively evaluate candidate targets including disease associations and druggablity and develop target data packages
- Generate proposals for target prioritization in close collaboration with data scientists and other subject matter experts
- Provide thought leadership and guidance on obesity T2D and cardiovascular diseases biology staying abreast of emerging trends and advancements in the field
- Generate design proposal and feasibility assessment for target validation using Valos tissue and cellular disease models in collaboration with Valos tissue and cell model experts and/or leveraging CRO
- Contribute to improvements of target discovery and prioritization processes
- Provide guidance and feedback on research proposals aimed at discovering targets for obesity or cardiovascular diseases
What You Bring
- A PhD in Biological Sciences or related fields with 10 years of experience and deep expertise in one or more of the following areas: obesity cardiovascular diseases inflammation metabolism
- 5 years of experience in drug discovery and track record of impactful contributions to drug discovery programs and/or target evaluation and/or validation
- Strong oral and written communication presentation and interpersonal skills
- Experience in successfully collaborating with data scientists/computational biologists to achieve specific goals
You May Also Bring
- Experience in the development of target evaluation criteria and prioritization strategies for large numbers of potential targets
- Track record of success as a target champion
More on Valo
Valo Health LLC (Valo) is a technology company built to transform the drug discovery and development process using humancentric data and artificial intelligencedriven computation. As a digitally native company Valo aims to fully integrate humancentric data across the entire drug development life cycle into a single unified architecture thereby accelerating the discovery and development of lifechanging while simultaneously reducing costs time and failure rates. The companys Opal Computational Platform is an integrated set of capabilities designed to transform data into valuable insights that may accelerate discoveries and enable Valo to advance a robust pipeline of programs across cardiovascular metabolic renal oncology and neurodegenerative diseases. Founded by Flagship Pioneering and headquartered in Lexington MA. Valo also has offices in New York NY. To learn more visitwww.valohealth.
Required Experience:
Staff IC
Employment Type
Full Time
