Postdoctoral Associate Dr Loretta Li Lab

Ann & Robert H. Lurie Childrens Hospital of Chicago provides superior pediatric care in a setting that offers the latest benefits and innovations in medical technology research and familyfriendly design. As the largest pediatric provider in the region with a 140year legacy of excellence kids and their families are at the center of all we do. Ann & Robert H. Lurie Childrens Hospital of Chicago is ranked in all 10 specialties by the U.S. News & World Report.

*Mouse experience strongly preferred within this lab. Please ensure you have experience using mouse models*

Seeking a highly motivated postdoctoral fellow to join Dr. Loretta Lis laboratory at Lurie Childrens Hospital / Northwestern University. We are a recently established translational leukemia research laboratory that uses a variety of biochemical molecular and cell biology approaches to identify new therapeutic targets develop preclinical models of disease and test novel therapeutics both in vitro and in vivo using mouse models. Much of the labs work to date has focused on Philadelphia chromosome (Ph) like Bcell acute lymphoblastic leukemia. The successful candidate will be a team player capable of handling multiple tasks and adaptable to a fastpaced research environment.

• Familiarity with basic handling of DNA RNA and protein experience with molecular cloning CRISPR/Cas9 genome editing chromatin immunoprecipitation and retroviral / lentiviral work. Experience with programing and bioinformatics analyses of large genomic datasets would be an asset.
• Comfort with handling mice is required. This includes previous experience with or willingness to learn about the breeding and weaning of animals bleeding the mice tail vein injections IV IP and PO dosing and necropsy.
• At least 1 firstauthor publication is preferred
• 3 strong reference letters preferred
• Attention to detail in completing tasks and a strong work ethic is essential. This includes a willingness to critically read and keep up to date on the latest scientific literature logically troubleshoot problems and offer both intellectual and technical input during collaborative meetings.
• The candidate should have flexibility in their schedule to work on weekends and some evenings as needed to meet project goals.
• Working knowledge of computers ability to work independently and function as a team member is essential. Therefore experience in regular interaction with outside groups is highly desirable.
• Excellent ability to synthesize research findings for presentation in both oral and written formats.
• Strong organizational skills this includes the ability to establish priorities react promptly to a large variety of requests and the ability to keep the workplace clean and organized.

Job Duties:

The postdoctoral fellow will carry out an independent research project studying 1 the preclinical activity of novel JAK2 inhibitors 2 defining and validating mechanisms of resistance to targeted JAK2 inhibitors or 3 studying the role of the PRL2 phosphatase in TALL under the supervision of the principal investigator Dr. Loretta Li. The successful candidate will be responsible for the following :

• Provide researchers as requested with technical assistance.
• Performs job functions adhering to principals of innovation academic excellence and teamwork to provide the highest quality research effort to our Institution coworkers and others.
• Genetic studies molecular biology Redcap/ Imaging software gene chip arrays and others.
• Analyzing data.
• Preparing data for presentations grants and publications.
• Help write grant proposals and progress reports related to research projects.
• Participate in regular lab meetings journal clubs and research seminars.
• Designing and conducting laboratory experiments to advance the research progress in the lab.
• Skilled handling of mice as needed to meet project goals.
• Analyzing data and troubleshooting experiments as needed.
• Maintaining detailed records of their laboratory work results and data analyses.
• Preparing presentations for lab meetings journal clubs research seminars and research conferences.
• Synthesizing data and generating figures for grants manuscripts and presentations at the local national and international level.
• Working with the principal investigator to write grant proposals and progress reports related to the research project.
• Supervision and training of students and technicians in the lab.
• Sharing in the responsibilities of routine laboratory maintenance. Other job functions as assigned.
• Organizational skills: Ability to establish priorities and react promptly to a large variety of requestsand needs sometimes in stressful situations.

Knowledge Skills & Abilities:

• Ph. D. or MD in Medical or Biological Science Program.
• Knowledge in Computer programs word excel and power point presentations.
• Excellent writing and communication skills.

Education

Pay Range

At Lurie Childrens we are committed to competitive and fair compensation aligned with market rates and internal equity reflecting individual contributions experience and expertise. The pay range for this job indicates minimum and maximum targets for the position. Ranges are regularly reviewed to stay aligned with market conditions.In addition to base salary Lurie Childrens offer a comprehensive rewards package that may include differentials for some hourly employees leadership incentivesfor select roles health and retirement benefits and wellbeing programs. For more details on other compensation consult your recruiter or click the followinglink to learn more about our benefits.

Benefit Statement

For full time and part time employees who work 20 or more hours per week we offer a generous benefits package that includes:

Medical dental and vision insurance

Employer paid group term life and disability

Employer contribution toward Health Savings Account

Flexible Spending Accounts

Paid Time Off (PTO) Paid Holidays and Paid Parental Leave

403(b) with a 5 employer match

Various voluntary benefits:

• Supplemental Life AD&D and Disability

• Critical Illness Accident and Hospital Indemnity coverage

• Tuition assistance

• Student loan servicing and support

• Adoption benefits

• Backup Childcare and Eldercare

• Employee Assistance Program and other specialized behavioral health services and resources for employees and family members

• Discount on services at Lurie Childrens facilities

• Discount purchasing program

Theres a Place for You with Us

At Lurie Childrens we embrace and celebrate diversity and equity in a serious way. We are committed to building a team with a variety of backgrounds skills and viewpoints recognizing that diverse identities strengthen our workplace and the care we can provide to the Chicago community and beyond. We treat everyone fairly appreciate differences and make meaningful connections that foster belonging and allyship. This is a place where you can be your best so we can give our best to the patients and families who trust us with their care.

Lurie Childrens and its affiliatesare equal employment opportunity employers. We value diversity and are committed to creating an inclusive environment for all employees. All qualified applicants will receive consideration for employment without regard to race color sex sexual orientation gender identity or expression religion national origin ancestry age disability marital status pregnancy protected veteran status order of protection status protected genetic information or any other characteristic protected by law.

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