drjobs RESEARCH FELLOW - Immunology

RESEARCH FELLOW - Immunology

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Job Location drjobs

Phoenix, AZ - USA

Monthly Salary drjobs

Not Disclosed

drjobs

Salary Not Disclosed

Vacancy

1 Vacancy

Job Description

Description

The Gounari Lab Dr. Gounari Fotini Bio explores the molecular processes that govern normal T cell development and the deregulation of these processes in inflammatory diseases and cancer. Our research focuses on the dynamic functions of TCF1 a contextdependent transcription and epigenetic regulator. TCF1 a T cellspecific DNAbinding protein plays multiple stage and lineagespecific epigenetic roles during T cell development. While TCF1s critical roles in T cell biology is well established significant gaps remain in our understanding of how TCF1 orchestrates these functions across different developmental stages and cellular contexts.

To address these questions we have developed novel animal models that allow forauxininducible shortterm degradation of TCF1in vivo. These models enable us to study the molecular and epigenetic changessuch as chromatin accessibility 3D chromatin structure gene expression and developmental progressionthat occur when TCF1 is acutely depleted and later restored. We are now seeking ahighly motivated postdoctoral researcherto join our lab and contribute to this exciting area of research.

Key Responsibilities:

Interested applicants are required to submit a CV a brief cover letter describing their research experience and interests and contact information for at least two references.

A Research Fellow at Mayo Clinic is a temporary position intended to provide training and education in research. Individuals will train in the research program of a Mayo Clinic principal investigator. Qualified individuals will demonstrate the potential for research as evidenced by their training and peerreviewed publications and should become competitive for national research grants. Proof of English proficiency is required for J1 ShortTerm Scholars Research Scholars Professors Specialists and Student Interns sponsored by Mayo Clinic.



Qualifications
  • Ph.D. in molecular biology epigenetics immunology or a related field.
  • Strong expertise inchromatin accessibility assays3D chromatin structure analysis andgene expression profiling(e.g. RNAseq).
  • Experience with animal models and/or T cell biology is highly desirable.
  • Strong problemsolving skills ability to work independently and interest in collaborative research.
  • Excellent written and oral communication skills.


Employment Type

Full-Time

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