Senior Scientist In Vivo Cardiovascular Biology
Senior Scientist In Vivo Cardiovascular Biology
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Job Description
Do you have expertise within In Vivo cardiovascular biology and enjoy working in the lab Would you like to apply your expertise in a global company that is accelerating innovative science and turning ideas into lifechanging medicines Join us to shape the future of Cardiovascular Renal and Metabolic (CVRM) treatments!
CVRM is one of AstraZenecas key research areas with a patientfocused approach to discovering treatments for cardiovascular renal and metabolic diseases advancing candidate to latestage development. Our team identifies and validates drug targets for cardiovascular disease exploring their efficacy and mechanisms. Join us to contribute to drug discovery and development at every phase.
Were now hiring a Senior Scientist in cardiovascular biology for our Bioscience Cardiovascular Divisions In Vivo team in Gothenburg Sweden.
Accountabilities
As a Senior Scientist in In Vivo Cardiovascular Biology at AstraZeneca you will be pivotal in advancing cardiovascular science and projects. This labbased role involves exploring novel drug targets and supporting existing projects with critical In Vivo data. You will collaborate extensively with scientists and teams across diverse functions at AstraZeneca as well as with external partners.
Your work will involve using various rodent disease models to independently design develop and run In Vivo studies from pretarget identification to clinical stage advancements. You will have the chance to establish new methods and trial novel techniques to enhance current portfolios and novel science.
Key Responsibilities:
Develop and run rodent treadmill protocols
Perform invasive hemodynamic recordings including ventricular pressurevolume loops and In Vivo blood pressure and heart rate monitoring.
Conduct rodent cardiovascular surgical procedures such as aortic constriction surgery myocardial infarction induction via permanent LAD ligation and implantations of osmotic mini pumps and intravascular catheters.
Perform cardiac echocardiography using the VisualSonics Vevo system and analyze and interpret echocardiographic parameters.
Analyze and interpret generated data independently and communicate findings to project teams departments and at external meetings.
Collaborate across Bioscience and other AstraZeneca functions to fulfill key project activities and contribute to scientific communications via journal publications and meetings.
Foster a dynamic innovative environment where new ideas and improvements are welcomed and shared.
You may take on responsibilities as a biology lead in drug projects identifying and championing novel drug targets to become new projects.
Essential Skills/Experience
PhD or MSc degree in biology pharmacology cardiovascular disease or similar
Strong experience with independent design development and of In Vivo studies for projects from pretarget identification to clinical stage within the cardiovascular area
Hands on experience with rodent surgical procedures within the cardiovascular area
Hands on experience with rodent treadmill protocols
Excellent English communication skills both spoken and in writing
Entrepreneurial and flexible ways of working
Great collaboration skills
Strong drive and commitment
Desirable Skills/Experience
Background in drug discovery and development within the pharmaceutical industry
At AstraZeneca we thrive in an environment where the brightest minds come together in an inclusive culture. We are committed to making a difference by fusing data and technology with scientific innovations to achieve breakthroughs. Our collaborative approach unites academia biotechs and industry experts to create the greatest impact on disease. Here you can build a meaningful career while pushing the boundaries of science to deliver lifechanging medicines.
Ready to make a significant impact Apply now to join our team!
Welcome with your application no later than March 20th 2025
Date Posted
10mars2025Closing Date
20mars2025Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion starting with our recruitment process. We welcome and consider applications from all qualified candidates regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations please complete the section in the application form.Required Experience:
Senior IC
Employment Type
Full-Time
