Scientist III
Scientist III
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Not Disclosed
Salary Not Disclosed
1 Vacancy
Job Description
MacroGenics is a leader in the discovery and development of innovative medicines that utilize our next generation antibodybased technologies. Our team of350 dedicated individuals is advancing a pipeline of product candidates to treat patients with cancer.Our products and platforms have attracted multiple partnerships with leading pharmaceuticaland biotechnologycompanies around the globe.
The Company considers its employees to be its most valuable asset and we are committed to providing opportunities for individuals to learn and grow as a means to further their professional development. MacroGenics corporate culture promotes an atmosphere of innovation open communication and teamwork where employees can see firsthand how they contribute to the success of the organization.
Summary of Position
This position is part of the Protein Science group within the Research department. The Scientist I/II will be responsible for the analysis of biomolecular interactions using Surface Plasmon Resonance (SPR) and Biolayer Interferometry (BLI) to analyze biomolecular interactions primarily focusing on antibodyantigen binding kinetics in support of the biologics research pipeline. Additional roles include the purification of recombinant proteins and their characterization by HPLC and capillary electrophoresis.
Responsibilities and Job Duties
- Design execute and analyze SPR and BLI experiments to determine antibody affinities kinetics and epitopes.
- Maintain SPR and BLI instruments
- Purify proteins and perform routine analytical characterization
- Confirm protein identity by Liquid ChromatographyMass Spectrometry (LCMS)
- Conduct protein stability tests for lead molecule selection
- Maintain timely and accurate records
Minimum Qualifications
Scientist I
Education & Other Credentials
- Bachelors (BS/BA) in Biochemistry or a related scientific field of study with 3 years of benchrelated experience within industry and/or academia.
OR
- A Masters degree in Biochemistry or a related scientific field of study with 0 years of benchrelated experience within industry and/or academia.
Scientist II
Education & Other Credentials
- Bachelors (BS/BA) in Biochemistry or a related scientific field of study with 5 years of strong benchrelated experience within industry and/or academia.
OR
- A Masters degree in Biochemistry or a related scientific field of study with 2 years of strong benchrelated experience within industry and/or academia.
Knowledge Skills and Abilities
- Understanding of biophysical principles governing proteinprotein interactions and binding kinetics
- Handson experience with SPR and BLI instruments
- Ability to handle multiple tasks and willing to collaborate with other teams
- Excellent written and verbal communications skills
- Maintain timely and accurate records
Supervisory Responsibilities:
No.
Preferred Knowledge and Skills
- Knowledge and experience about protein purification
- Handon experience with AKTA chromatography system preferred
- Handon experience with HPLC or LCMS preferred
Additional Information
The annual rate of pay for this position ranges from $84400 $128800 (Scientist I) and $94300 $143800 (Scientist II). For nonexempt roles and according to applicable regulations there may be the possibility for overtime pay. This role is eligible for the Companys discretionary bonus and discretionary equity incentives. Eligible employees may participate in the Companys benefits programs including medical / dental / vision / prescription coverage employee wellness resources 401(k) plan with employer match access to an Employee Stock Purchase Plan (ESPP) paid time off & paid parental leave benefits and disability benefits.
The annual pay rate range is described in good faith and the Company believes is the range of possible compensation for this role at the time of this posting depending on the candidates experience qualifications geographic location and other factors permitted by law. The Company may ultimately pay more or less than the posted range and this range may be modified in the future. No amount is considered to be wages or compensation until such amount is earned vested and determinable under the terms and conditions of the applicable policies and plans. The amount and availability of any bonus commission benefits or any other form of compensation and benefits that are allocable to a particular employee remains in the Companys sole discretion unless and until paid and may be modified at the Companys sole discretion consistent with the law.
Statement
MacroGenics is proud to be an equal opportunity employer. Employment selection and related decisions are made without regard to race color national origin sex gender identity sexual orientation religion age disability protected veteran status or any other characteristic protected by federal state or local law. We are committed to working with and providing reasonable accommodation to individuals with disabilities. If because of a medical condition or disability you need a reasonable accommodation for any part of the employment process please email or calland/or 711 for TTD/TTY service.
Equal Opportunity Employer/Veterans/Disabled
We do notaccept nonsolicited resumes or candidate submittals from search/recruiting agencies.
Employment Type
Full-Time
