Protein Biochemist Core Technologies
Protein Biochemist Core Technologies
Posted on :
17-03-2025
Employer Active
1 Vacancy
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Yearly Salary
$ 130000 - 180000
Vacancy
1 Vacancy
Posted on :
17-03-2025
Job Description
A Bit About Us:
We are Arcadia Science. Arcadia is a science company founded and led by scientists. Our mission is to transform evolutionary innovations into realworld solutions by openly developing more efficient replicable and sustainable ways to leverage the biology of diverse organisms.
The Opportunity:
We are seeking an experienced Protein Biochemist to join a proteinfocused team collaborating across the organization. This team creatively and iteratively implements scientific tools to solve biological research problems with a particular focus on predicting and testing protein functions.
In this role youll spearhead our efforts in biochemically characterizing proteins. Your core focus will be the expression purification and characterization of recombinant proteins and the development and optimization of downstream biochemical assays. Given the diverse array of proteins we work with including proteins of unknown function you will also need to spearhead troubleshooting of protein expression and purification workflows. You may also need to develop creative new assays for discovering new functions. Youll generally be responsible for providing expert knowledge and decisionmaking related to protein biology.
Our ideal candidate is a technical expert in protein biochemistry applied across various industrial and research contexts. The candidate should demonstrate a solid understanding of protein structurefunction relationships. As the lead experimentalist on our team you must be able to independently plan and execute projects.
Key Responsibilities:
- Design plan and execute recombinant protein expression and purification protocols for diverse proteins from a wide range of organisms
- Ensure purity and quality of resulting protein is appropriate for downstream applications
- Independently troubleshoot expression and purification challenges such as comparing orthologous expression systems increasing yields assessing and addressing insolubility and reviewing posttranslational modification needs
- Prepare proteins for functional testing in cellbased assays and in vivo assays by validating identity folded/oligomeric state and concentrations
- Work closely with experts to automate or develop higher throughput strategies for recurring biochemical workflows
- Develop optimize and implement both quantitative and qualitative biochemical assays for the screening and functional characterization of proteins
- Project manage contract work with outside consultants or CROs
- Collaborate closely with crossfunctional teams
- Keep detailed experimental records and documentation (SOPs) for all workflows
- Synthesize ideas data and findings into fully openaccess pubs
Qualifications:
- Ph.D. or equivalent experience in Biochemistry Biology Chemistry or a related field
- At least 1 year of fulltime relevant scientific experience postPhD
- Handson technical experience in the following areas: protein production systems (gmg scale) protein expression and purification basic biochemical and biophysical assays to characterize protein stability and folding
- Deep knowledge of protein function biology and structure
- Demonstrable experience troubleshooting challenging protein purifications
- Effective project management ability demonstrated by ability to scope work with key stakeholders create milestones and timelines identify blockers
- An excellent verbal and written science communicator for both general and technical audiences. We expect all scientists to actively draft and openly publish their lessons
Interested applicants should apply using the link below and include a CV cover letter and answers to the application questions.
The expected salary range is $130000$180000 per year with generous equity and benefits depending on experience level. The position will require the individual to be onsite at our Berkeley California headquarters. We will review applications on a rolling basis and the job will remain open until the position is filled.
Arcadia Science is an equal opportunity workplace; we welcome people from all backgrounds and communities. We provide competitive compensation and practical benefits to keep you happy and healthy so that you can do your best work. Please note that an offer of employment from Arcadia is contingent upon the successful clearance of a reference and background check.
Employment Type
Full-Time
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