PostDoc Position in Extracellular Vesicle Biology (mfd)
Weilheim-Schongau - Germany
Job Summary
At Roche you can show up as yourself embraced for the unique qualities you bring. Our culture encourages personal expression open dialogue and genuine connections where you are valued accepted and respected for who you are allowing you to thrive both personally and professionally. This is how we aim to prevent stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche where every voice matters.
We are looking for a highly motivated and talented Postdoctoral Fellow (m/f/d) to join our Discovery Sciences this role you will be at the forefront of Science enriching and analyzing Extracellular Vesicles (EVs) in order to deduce a diagnostic potential and address different medical needs. Your responsibilities will encompass the design execution and analysis of wet-lab experiments.
This position is embedded within the Discovery Sciences Chapter at Roche Diagnostics GmbH. As part of the Technology Program you will join a high-impact team of researchers dedicated to pioneering next-generation diagnostic solutions.
Our culture is defined by trust transparency and a strong collaborative spirit. We are looking for a proactive colleague who balances independent critical thinking with team spirit and the flexibility to collaborate across diverse departments and interdisciplinary teams.
- Perform the enrichment of EVs from human matrices predominantly via immunoprecipitation but also other methods like SEC dUC and AF4.
- Analysis and quality assessment of the enriched EVs with different state-of-the-art methods and technologies (targeted and untargeted like mass spectrometry RNA sequencing luminescence) in cooperation with other departments
- Partner with bioinformatics assay development and sequencing teams to evaluate the applicability of the captured EVs for diagnostic platforms.
- Drive interdisciplinary meetings to share data leverage expertise across functions and contribute to the broader Diagnostics strategy.
- Document findings for patent filings and present research in stakeholder meetings scientific journals and international conferences.
- You have successfully completed a PhD in Molecular Biology Biochemistry Cell Biology or a related field including 3 years of experimental research experience and a strong track record of peer-reviewed publications.
- You have deep expertise in the biology enrichment and analysis of Extracellular Vesicles as well as the respective laboratory techniques such as immunoprecipitation size exclusion chromatography asymmetrical flow field-flow fractionation and immunoassays like ELISA and Western Blot
- Your profile is complemented by proficiency in working with nucleic acids like RNA isolation and RNA sequencing.
- Your knowledge and application of statistical concepts is considered a plus
- You are goal-oriented and eager to establish new wet-lab techniques and scientific concepts
- Your personal drive and your ability to learn and take over responsibility is a key value for us.
- You possess excellent communication skills and fluency in English
This position requires handling of human fluid samples i.e. potentially infectious material (Biosafety Level 2 Infektionsschutzgesetz) under company safety standards.
When does it start
This position should be filled with effect January 2027 and is limited to 2 years.
Are you interested in joining us
- Candidates with strong applications will be invited to a telephone or virtual interview.
- Following a successful initial interview the final evaluation step involves an in-person interview and presentation in Penzberg.
Please submit your application by sending an updated CV (including publication list and references) together with your latest certificates. Before sending your application please note that no further documents can be added subsequently.
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About Company
F. Hoffmann-La Roche AG is a Swiss multinational healthcare company that operates worldwide under two divisions: Pharmaceuticals and Diagnostics. Its holding company, Roche Holding AG, has bearer shares listed on the SIX Swiss Exchange. The company headquarters are located in Basel.