PhD Development of a Novel Lab-on-a-Chip Component for the Analysis and Sorting of Single Cells

As part of our research team you will work on cutting-edge solutions for the life sciences. We are offering a PhD position to develop a novel dielectrophoresis (DEP) chip for the analysis and sorting of single cells.
Multi-omics analyses at the single-cell level offer crucial diagnostic insights into diseases. However current automation technologies are often inefficient and expensive. Your project will focus on overcoming these limitations by developing an image-based DEP chip to automate the compartmentation sample preparation analysis and sorting of single cells. This technology aims to enable high-throughput gentle multi-omics analyses for universal sample types.

• You will develop and evaluate innovative concepts for semiconductor-based dielectrophoresis (DEP) chips determining robust electrical microfluidic and thermal operating parameters.
• Furthermore you will investigate the physical limits of chip miniaturization and explore feasible manufacturing routes compatible with Boschs CMOS technology.
• You will design and fabricate a functional demonstrator using semiconductor manufacturing processes and integrate it into a microfluidic system.
• Last but not least you will characterize the prototype and perform a proof of concept for all operating modes using a representative bioassay with living cells in physiological media.

Qualifications :

• Education: excellent Masters degree in Electrical Engineering Microsystems Engineering Biomedical Engineering Physics or a comparable field
• Experience and Knowledge: detailed knowledge of classical MEMS microfluidics and biomedical engineering; expertise in microfluidic and electrical design for lab-on-chip systems; experience in modeling of physical cell interactions at the microscale; knowledge of (optical) signal processing; experience with cleanroom processes and knowledge of oncology are advantageous
• Personality and Working Practice: you actively contribute your ideas and communicate your research results clearly and convincingly; your curiosity motivates you to explore new approaches and you enjoy taking a hands-on role; you work in a structured manner to achieve your goals develop creative solutions to complex challenges and independently conduct experiments
• Languages: very good written and spoken German and English

Additional Information :

final topic depends on your university.

Start: Oktober 2026

Diversity and inclusion are not just trends for us but are firmly anchored in our corporate culture. Therefore we welcome all applications regardless of gender age disability religion ethnic origin or sexual identity.

Need support during your application
Celina Dannecker (Human Resources)
49 6

Need further information about the job
Raphaelle Satet (Functional Department)
 49  
 

Work #LikeABosch starts here: Apply now!

Remote Work :

No

Employment Type :

Full-time