Postdoc in Genetic Tool Development in iPSC-derived Neural Systems DTU Bioengineering

Do you want to be part of a team developing next-generation genetic tools for therapies targeting neurological diseases

Then join the Precision Medicine Technologies Lab at the Department of Biotechnology and Biomedicine Technical University of Denmark (DTU) for afully funded 4-year postdoc position. In our team you will design synthetic promoter libraries and screen them in human iPSC-derived neural cell types. Moreover you will use molecular and cell biology techniques such as FACS and barcode sequencing to evaluate and optimize identified regulatory sequences. Your work will help create highly precise genetic medicines for neurological diseases such as developmental and epileptic encephalopathies.

Responsibilities and qualifications
We are looking for anambitious and highly motivated postdoc with a strong background in biotechnology biomedical engineering molecular biology stem cell biology or a related field. You will work under the supervision of Assistant Professor Lisa Riedmayr on the development of a pipeline for creating synthetic promoters that enable precise targeting of neural cell types.

You will work with a wide range of methods includingmolecular cloninglentivirus productionhuman iPSC culture and differentiationhigh-throughput screeningFACSnext-generation sequencing andcomputational taskssuch as library design and sequencing data analysis.

The main tasks include:

• Design and generation of pooled promoter libraries
• Culture and differentiation of human iPSCs into neural cell types
• Performing and analysing high throughput screens
• Evaluation of promoter activity using FACS NGS and barcode sequencing
• Optimization of regulatory sequences
• Contributions to ./. student supervision

Essential qualifications:

• Hold a PhD degree in biotechnology biomedical engineering molecular biology stem cell biology or a related field
• Be ambitious curious and highly motivated
• Have the persistence to work on challenging tasks and succeed in a competitive research field
• Have the ability to work in a team as well as independently
• Have excellent communication skills in written and spoken English
• Broad background knowledge in genetic tool development e.g. construction and cloning of pooled libraries and high-throughput screens
• Hands-on experience with human iPSC culture and differentiation into neural cells
• Practical experience with cloning techniques and flow cytometry or FACS
• Basic bioinformatic skills

Additional desirable but not essential qualifications:

• Experience in promoter design cis-regulatory elements enhancer biology or transcriptional regulation
• Experience with CRISPR-Cas technologies or other genome engineering approaches

As a formal qualification you must hold a PhD degree (or equivalent).

We offer
DTU is a leading technical university globally recognized for the excellence of its research education innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility.

Salary and terms of employment
The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union.

The period of employment is 4 years.

Starting date is September 1^st 2026 (or according to mutual agreement). The position is a full-time position.

You can read more aboutcareer paths at DTU here.

Further information
Further information may be obtained fromAssistant Professor Lisa Maria Riedmayr ().

You can read more about theDepartment of Biotechnology and Biomedicine at about the Precision Medicine Technologies lab at you are applying from abroad you may find useful information on working in Denmark and at DTU atDTU Moving to Denmark.

Application procedure
Your complete online application must be submitted no later than 29 June 2026 (23:59 Danish time).

Applications must be submitted as one PDF file containing all materials to be given consideration. To apply please open the link Apply now fill out the online application form and attach all your materials in English in one PDF file. The file must include:

• Application (cover letter)
• CV
• Academic Diplomas (MSc/PhD in English)
• List of publications

Applications received after the deadline will not be considered.

All interested candidates irrespective of age gender disability race religion or ethnic background are encouraged to apply. As DTU works with research in critical technology which is subject to special rules for security and export control open-source background checks may be conducted on qualified candidates for the position.

The Department of Biotechnology and Biomedicine (DTU Bioengineering)is an international leader in the areas of biotechnology and biomedicine. Our engineering approach to all aspects of biotechnology and biomedicine positions us as a valuable player with unique competences in a growing bio-based economy and with health systems transforming towards personalized medicine. We have a clear focus on the needs in the life science- and biotech industries and point towards innovation new businesses and scientific services for the benefit of society. The department has extensive collaborations with national and international research units and industry. DTU Bioengineering has approx. 400 employees of which 2/3 are scientific department is located at DTU Lyngby Campus.

DTU For the benefit of society since 1829
DTU is one of Europes leading elite technical universities. Through research and education at an international top level we create solutions to the major societal challenges of our time and help secure Europes global leadership in sustainable technological development. Since Hans Christian Ørsted founded DTU almost 200 years ago our mission has remained the same: We develop and create value through the natural and technical sciences for the benefit of society. DTU has 13800 students 1600 PhD students and 6500 employees. We work in an international environment and have an inclusive stimulating and informal work culture. DTU has campuses in all parts of Denmark and in Greenland and collaborates with the best universities around the world.