PhD scholarship in engineering food safe chassis strains BRIGHT

Are you excited by the challenge of engineering fungal cells to become the foundation of a new global food category Passionate about combining genetic tools with fermentation science to make food-grade chassis measurably safer Interested in working in a rapidly growing interdisciplinary research environment tackling food-system challenges Then join us as our new PhD Student in Microbial Strain Engineering!

This position is a part of BRIGHTs mission- oriented Microbial Food research programme (referred to as Mission 2) which aims to build an AI-powered framework for the rational design of microbial foods that meet four targets: consumer acceptance health sustainability and scalability. The first phase focuses on two fungal chassis Aspergillusand Yarrowia characterizing more than 500 prototypes through multi-omics sensory analysis life-cycle assessment and safety testing. Predictive models for flavor texture nutrition and process scale-up are trained iteratively through active learning. The scientific scope spans strain engineering adaptive laboratory evolution solid- and liquid-state fermentation sensory and consumer research and pre-clinical and clinical evaluation of safety bioavailability and cardiometabolic health in collaboration with national and international partners.

You will work with regulatory and food safety experts and interact closely with strain engineering colleagues across BRIGHT and DTU to attenuate biosynthetic gene clusters implicated in toxin production and to tune fermentation conditions that suppress secondary-metabolite formation. The engineered chassis and process variants you deliver will feed directly into the food prototype development providing a basis for next generation sustainable and healthy microbial foods.

The job
As our PhD Student in Microbial Strain Engineering you will:

• Design and execute genetic edits in filamentous fungi (Aspergillus) to attenuate biosynthetic gene clusters associated with mycotoxin production
• Characterize the resulting strains phenotypically and analytically in tight coordination with the safety and analytical chemistry workstream
• Investigate how fermentation conditions modulate secondary-metabolite formation and identify combinations of genetic and process changes that reproducibly reduce risk
• Contribute to the delivery of toxin-attenuated strain variants suitable for downstream prototype development

What were looking for
You will have a two-year Masters degree (120 ECTS points) in microbiology food science molecular biology synthetic biology mycology or a related disciplineor a similar degree with an academic level equivalent to a two-year Masters degree.

You will have excellent organizational and project management skills and enjoy developing new methods.

You will be fluent in spoken and written English and have literacy in common IT systems.

The ideal candidate will also:

• have experience with CRISPR-based editing tools and/or homologous recombination strategies in microorganisms
• have familiarity with secondary-metabolite biosynthesis and biosynthetic gene cluster analysis
• have some exposure to fermentation and/or bioprocess development
• be able to work both independently and as part of a large collaborative team
• be comfortable in an interdisciplinary environment spanning genetics chemistry fermentation and regulatory science
• be patient meticulous curious and collaborative key qualities for engineering work in a shared platform
• strong desire for utilizing AI in the development of your research

Approval and Enrolment
The scholarship for the PhD degree is subject to academic approval and the candidate will be enrolled in one of the general degree programmes at DTU. For information about our enrolment requirements and the general planning of the PhD study programme please see DTUs rules for the PhD education.

Assessment

The assessment of the applicants will be made by Prof Morten Sommer.

We offer
DTU is a leading technical university globally recognized for the excellence of its research education innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility.

Salary and appointment terms
The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union.

The period of employment is 3 years full time. Start dateor according to mutual agreement.

You can read more about career paths at DTU here.

Further information
For additional information about the position please contact Prof Morten Sommer at

You can read more about BRIGHT below and at

If you are applying from abroad you may find useful information on working in Denmark and at DTU at DTU Moving to you have the option of joining our monthly free seminar PhDrelocation to Denmark and startup Zoom seminar for all questions regarding the practical matters of moving to Denmark and working as a PhD at DTU.

Application procedure
Your complete online application must be submitted no later than27 September 2026 (23:59 Danish time).

Applications must be submitted as one PDF file containing all materials to be given consideration. To apply please open the link Apply now fill out the online application form and attach all your materials in English in one PDF file. The file must include:

• A letter motivating the application (cover letter)
• Curriculum vitae
• Grade transcripts and BSc/MSc diploma (in English) including official description of grading scale
• One letter of reference with referees email and phone number

You may apply prior to obtaining your masters degree but cannot begin before having received it.

Applications received after the deadline will not be considered.

All interested candidates irrespective of age gender disability race religion or ethnic background are encouraged to apply. As DTU works with research in critical technology which is subject to special rules for security and export control open-source background checks may be conducted on qualified candidates for the position.

As DTU works with research in critical technology which is subject to special rules for security and export control open-source background checks may be conducted on qualified candidates for the position.

BRIGHT Mission 2: Microbial Foods
BRIGHT Mission 2 aims to build an AI-powered framework for the rational design of microbial foods that meet four targets: consumer acceptance health sustainability and scalability. The first phase focuses on two fungal chassisAspergillusandYarrowia characterizing more than 500 prototypes through multi-omics sensory analysis life-cycle assessment and safety testing. Predictive models for flavor texture nutrition and process scale-up are trained iteratively through active learning. The scientific scope spans strain engineering adaptive laboratory evolution solid- and liquid-state fermentation sensory and consumer research and pre-clinical and clinical evaluation of safety bioavailability and cardiometabolic health in collaboration with national and international partners.

BRIGHT The Novo Nordisk Foundation Biotechnology Research Institute for the Green Transition
The Novo Nordisk Foundation Biotechnology Research Institute for the Green Transition (BRIGHT) is a major initiative based at DTU that aims to accelerate the development of biosolutions and strengthen the bio-based economy. BRIGHT serves as a hub for academic and industrial partners working together to unlock the potential of bioproduction. BRIGHT focuses on three main areas: Sustainable materials (Developing bio-based alternatives to fossil-derived materials) Microbial foods (Innovating food production through microbial technologies) and Microorganisms for net-zero agriculture (Creating solutions to reduce greenhouse gas emissions in agriculture). The goal is to develop and scale innovative biosolutions within these areas ultimately creating sustainable and competitive alternatives to fossil-based products and processes that can make significant contributions to reducing global greenhouse gas emissions.

DTU For the benefit of society since 1829
DTU is one of Europes leading elite technical universities. Through research and education at an international top level we create solutions to the major societal challenges of our time and help secure Europes global leadership in sustainable technological development. Since Hans Christian Ørsted founded DTU almost 200 years ago our mission has remained the same: We develop and create value through the natural and technical sciences for the benefit of society. DTU has 13800 students 1600 PhD students and 6500 employees. We work in an international environment and have an inclusive stimulating and informal work culture. DTU has campuses in all parts of Denmark and in Greenland and collaborates with the best universities around the world.