Postdoc Product development

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The role

We are seeking a talented Postdoctoral Scholar (Postdoc) to work in a highly collaborative environment for a twoyear assignment during which you will explore advanced in vitro characterization methods that connect lipid formulation behavior to drug delivery potential ultimately aiming to design nextgeneration lipid based formulation strategies for beyond rule of five (bRo5) drug candidates.

Key responsibilities

In this role you will:

• Build and explore an advanced in vitro characterization toolbox e.g. coupling dissolution lipolysis precipitation/crystallization mucus penetration and permeation readouts for lipidbased formulations.
• Explore downscaling/highthroughput feasibility for e.g. lipolysis and dissolutionpermeation workflows to enable efficient screening and optimization.
• Design and optimize nextlevel lipid formulation strategies for the oral delivery of bRo5 molecules
• Support in vivo translation e.g. contributing to rat PK/lymphatic transport studies and mechanistic experiments
• Communicate scientific outcomes through internal presentations and scientific forums and contribute to manuscript preparation and publication strategy consistent with IP guidance.

Required qualifications

• PhD (or near completion) in Pharmaceutical Sciences Chemical Engineering Chemistry Bioengineering or a closely related discipline.
• Demonstrated ability to design and execute experimental research with scientific independence (literature review planning lab execution data analysis reporting).
• Experience relevant to the project focus: lipidbased formulations and/or biopharmaceutics tools that link formulation behavior (dispersion/dissolution/digestion/precipitation) to delivery potential (permeation).
• Strong written and verbal communication skills in English and a track record of scientific output (publications/presentations and/or patents).
• Willingness to work onsite in Beerse Belgium with handson lab activities.

Preferred qualifications

• Experience with one or more of: lipolysis/digestion models dissolutionpermeation methods membrane permeability models (e.g. PAMPA variants) mucus assays precipitation/crystallization analytics or phase characterization during digestion/dissolution.
• Familiarity with lipid-based formulation optimization strategies and/or exploration of insilico tools to guide formulation design (e.g. COSMO).
• Exposure to translational modeling and/or in vivo study support (PBPK/PK; oral absorption/lymphatic transport).
  
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Required Skills:

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The anticipated base pay range for this position is:

Benefits:

In addition to base pay we offer the following benefits*: an annual bonus with set target (% of pay) depending on pay grade / location where the actual amount is based on the employees and companies performance of the previous calendar year or sales commissions. Moreover we offer vacation days parental leave for a minimum of 12 weeks bereavement leave caregiver leave volunteer leave well-being reimbursement programs for financial physical and mental health. We also offer service anniversary and recognition awards and subject to the terms of their respective plans employees - and in some locations eligible dependents - can participate in several insurance plans. For more information visit Employee benefits Supporting well-being & career growth Johnson & Johnson Careers.

*This is for informative purposes only. Amounts and actual benefits may vary by location and are subject to change.