Dynamic Biosensors

Dynamic Biosensors (DBS) develops and markets innovative technologies for studying complex molecular interactions and kinetics, supporting drug discovery in the pharma and biotech industries, as well as in basic and medical research. The new Dynamic Biosensors heliXcyto instrument performs single-cell Interaction Cytometry (scIC) for kinetic measurements directly on cells, retaining the molecules’ native membrane environment. The heliX+ instrument utilizes switchSENSE® technology, employing DNA nanolevers to functionalize molecules of interest on the chip surface to characterize their binding behavior and kinetics, as well as conformational changes. In combination with Bruker’s high-throughput SPR portfolio, which includes the all-new SPR #64 ‘Triceratops’ , and the 24- and 32-spot Sierra-Pro SPR systems, the combined Bruker Biosensors business now offers one of the most innovative range of instruments, workflows, and consumables for studying inter-molecular and molecular-cell interactions in the drug discovery pipeline.