Scientist – Peptide Chemistry

Scientist Peptide Chemistry

Location: Cambridge UK

Salary: Competitive Excellent Employee Benefits!

Introduction to the role:

AstraZeneca is a science-led global biopharmaceutical company with a focused portfolio in core therapies. At AstraZeneca we turn ideas into life changing medicines. We are committed to improving the health and lives of people across the globe through our research and development platform and a growing late-stage pipeline. Working in over 100 countries we have strength in emerging markets and our medicines are used by millions of patients and clinicians worldwide. Working here means being results-oriented and working together to make the impossible a reality.

We are seekinga skilled and enthusiastic peptide chemist to join our dynamic Peptide Discovery team. Situated at the Discovery Centre in Cambridge you will be part of a chemistry team developing the next generation of peptide medicines.

About the role:

In this laboratory-based role you willapply peptide chemistry knowledge to support our Early Discovery projects. We are looking for someone who has agoodunderstanding and background in solid-phase synthesis to support delivery of our peptide this laboratory-based position youwill contribute to the design synthesispurificationand analytical characterisation of peptides working either independently or inclose collaboration with other scientists.

This role requires a background in peptide chemistry problem-solvingskillsand the ability to work in a fast-paced collaborative environment. As part of a growing team you willbenefitfromnumerouspersonal and professional development opportunities at AstraZeneca.

Key responsibilities:

• Conduct laboratory-based experimental work in peptide chemistry to support project and platformobjectiveswithin the Peptide Discovery team.
• Design and synthesize peptides using solid-phase peptide synthesis (SPPS) techniques using both automated peptide synthesisers and manualmethods.
• Cleavage of peptides from resin supports purification by preparative HPLC and analysis using mass spectrometry techniques.
• Identifytroubleshootandhelpresolve synthetic and analytical challenges.
• Document experimental work accurately andin a timely mannermaintainingappropriaterecordsin line with company standards.
• Communicate results clearly through presentations data summaries reports and discussion with colleagues and project team members.
• Contribute to multi-disciplinary research and drug developmentand collaborate effectively withinmatrixteams building productive working relationships.
• Maintain and develop scientific knowledge by keeping up to date with literature methodologies and advances in peptide chemistry and related disciplines.