Scientist ADQC CMC
Scientist ADQC CMC
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Job Description
ProQR Therapeutics is a biotechnology company listed on NASDAQ with offices in Leiden, the Netherlands and Cambridge, Massachusetts, ProQR is focused on the development of life-changing RNA therapies to meet the unmet need of individuals and families with common and rare A team of 120 enthusiastic ProQRians from all walks of life and more than 30 different nationalities is up to this We have the passion and commitment to make a difference in the lives of the communities we Our proprietary Axiomer RNA editing technology platform enables the editing of specific single nucleotides in RNA using the cell s own editing Axiomer RNA editing technology harnesses ADAR (Adenosine Deaminase Acting on RNA), which is machinery present in all human cells to repair G-to-A mutations, modulate protein, and enable protective mutation Axiomer could potentially yield a new class of innovative medicines and treat currently untreatable
Our Chemistry, Manufacturing and Control (CMC) Department is currently looking for a Scientist (Full-time) with a passion for analytical chemistry to join our team in The CMC department has a central role within the ProQR Therapeutics organization and is responsible for developing, manufacturing, and characterizing oligonucleotides and therapeutic formulations for research, clinical development and
The Role
The scientist will support the in-house laboratory activities of the Analytical team, which is part of the CMC
The successful candidate is enthusiastic about bench work and will work closely with other researchers/scientists in an interdisciplinary team environment to progress activities related to the production of oligonucleotides which includes:
- Analytical method development and validation
- Writing of technical protocols and reports
- Execution of analytical testing (liquid chromatography, mass spectrometry, UV-Vis, endotoxins, Physico-chemical characteristics)
- Accountable for the planning of activities and delivery to meet project milestones
- Preparation, or revision, of standard operating procedures (SOPs)
- Identification and implementation of continuous improvement opportunities
- General lab activities such as equipment maintenance and inventory management
Required qualifications:
- in analytical chemistry or related discipline, or Master s with 3 years of experience, or a Bachelor s degree with 5+ years of pharmaceutical industry
- Strong laboratory skills and a high degree of attention to detail
- Experience with analytical techniques such as UPLC or HPLC, mass spectrometry, endotoxin testing, osmolality, and UV-Vis spectroscopy
- Proficient in spoken and written English
- Responsible with a proactive attitude who can work independently
- Being flexible, analytical, and well-organized
- A team player
Preferred:
- Experience in method development and validation
- Knowledge of GMP practices and pharmacopeial methods
- Experience with oligonucleotides is a plus
- Should enjoy challenging situations and have the flexibility to work in a dynamic and fast-moving environment where there is the freedom to
ProQR as an employer
As an employer, we are a true believer in the value of a workforce in which people from diverse backgrounds are encouraged to develop themselves, personally and We believe that happy and energized people, working well together in an environment in which they thrive, will do phenomenal and awesome
We are committed to ensuring that no employee, candidate, or job applicant receives less favorable treatment on the grounds of race, age, disability, pregnancy, religion, gender identity and expression, sexual orientation, marriage, or civil partnership At ProQR we want to create an inclusive culture where everyone can be valued for who they are and in which individual differences and contributions in all forms are recognized and
We offer an exciting and innovative working environment in a very committed organization, with the following benefits:
- A competitive salary
- 8% holiday allowance
- 30 vacation days
- An annual performance bonus
- Stock options
- A premium-free pension plan
- A commuting allowance
- A subsidized staff restaurant
- Flexible working arrangements
- Employee events (boot camp, Hipster caf , and other social events)
Do you want to be part of our devoted team of enthusiastic professionals? Do you think you can contribute to achieving our mission? Do you want to work in a challenging environment where your work can really make a difference? If so, we re looking forward to receiving your application by filling out our application
You can contact Silvia Catellani via if you have any
Please note that screening is part of our selection
Employment Type
Full Time
