ERC-funded postdoc position on inter-organelle communication during plant biotic stress responses
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ERC-funded postdoc position on inter-organelle communication during plant biotic stress responses
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Job Description
About the Lab/PSB
The VIBUGent Center for Plant Systems Biology (PSB) is a worldleading plant science institute located at the heart of a renowned Plant Biotech campus in Ghent Belgium. Its mission is to unravel plant biological processes and translate this knowledge into value for society. Please visit us at for more information.
Within the framework of an ERC Starting Grant the lab of Prof. Inge De Clercq (https:///groups/interorganellestresssignalling) aims to understand how plant cells perceive environmental signals (e.g. from attack by pathogens) and translate this into appropriate defence responses. We focus on studying the central role of intracellular organelles (mitochondria chloroplasts and the ER) in stress signal transduction and uncover the mechanisms of how these organelles communicate with each other through stressinduced contact sites. To this end we use interdisciplinary approaches by combining highend cell biology (confocal and superresolution microscopy) proteomics proximity labelling various other omics approaches and bioinformatics.
Job description
An ERC Starting grantfunded postdoc position is available in the group of Prof. Inge De Clercq at the VIBUGent Center for Plant Systems Biology (PSB) and Ghent University Belgium.
You will study interorganelle (between mitochondria chloroplasts and the ER) communication during the plants interaction with pathogens. Your project is embedded within the ERCSTG grant entitled COSI: Understanding organelle communication through COntact SItes in plant stress responses which studies the direct association between organelles through stressinduced contact sites by implementing stateoftheart cell biology and proteomics approaches. With this exciting project we seek to provide new mechanistic and functional insight into how stress signals are perceived and transduced between intracellular organelles and how they are translated into appropriate defence responses. You will design and implement tools to detect the dynamic (or reversible) association between organelles and use these tools to monitor contact site dynamics during various (biotic and/or abiotic) stress conditions using confocal microscopy and superresolution microscopy. In addition you will be involved in the characterization of the dynamic proteome at these stressinduced contact sites. You will also be involved in guiding a Ph.D. project focusing on this topic.
Profile
Essential
- You have a Ph.D. degree in Biotechnology Biochemistry Biology Bioengineering or equivalent.
- You are an expert in plant molecular biology and cell biology.
- You can plan and conduct research independently and accurately.
- You have a keen interest in organelle/cell biology proteomics intracellular signalling and plantpathogen interactions.
- You have excellent English communication skills.
Desirable but not required
- Experience from Ph.D. and/or postdoc in plant cell biology confocal microscopy superresolution microscopy proteomics and/or plantpathogen assays is a plus as well as a publication record in peerreviewed journals showing clear expertise in these areas.
- Experience in supervising Ph.D. students is not required but is also considered a plus.
Key personal characteristics
- You should work well in a team as you will be integrated into the international research environment of the VIBUGent Center of Plant Systems Biology and participate in international collaborations.
- You are proactive in establishing contacts with experts to solve problems and to communicate with other members of different team(s).
- You have a strong sense of responsibility and maintain a clean working environment.
We offer
- A 2year postdoc position with possibilities for prolongation and/or for applying for personal funding.
- An exciting and innovative project embedded in the ERCSTG 2020 grant COSI covering an interesting combination of stateoftheart techniques including cell biology (confocal microscopy monitoring dynamic proteinprotein interactions and (inter)organelle dynamics and highresolution microscopy) proteomics (proximity labelling based on TurboID protein pulldown) biochemistry plant stress assays and various omics approaches.
- A multidisciplinary and highly stimulating and supporting international research environment.
- Access to stateoftheart tools and infrastructure including core facilities for proteomics and superresolution microscopy.
- Various training opportunities are organized at VIB to broaden your expertise and skills (training.vib.be).
How to apply
Interested candidates are asked to apply online.
Additional requirements:
- A 1page summary of your motivation for the position your research experiences and future goals
- Detailed CV including publication list
- Contact information of 23 referees
in one PDF document.
The first review of applications will start immediately. A shortlist of applicants will be selected and invited for interviews.
The position remains open until a suitable candidate is found.
Employment Type
Full Time
