Executive Director, Automation, Robotics, and Technical Writing – Cell Therapy, Process Sciences, Analytics and Technology

If you have the passion and the drive to accelerate growth and make peoples lives better then AstraZeneca is the place for Operations we have a big ambition to deliver more medicines to patients quicker and more affordably. Backed by the investment leadership and a clear plan to get there we bring personal dedication and out of the box thinking.

AstraZeneca turns molecules to medicines bringing our Research & Development pipeline to life through a rigorous process of development manufacturing testing and delivery. Operations is accelerating fast. We are on track for Our Bold Ambition 2030 delivering 15 new medicines driving us forward across different modalities including biologics cell therapy ADCs and small molecules.

Position Summary

The Executive Director Automation Robotics and Technical Writing Cell Therapy Process Sciences Analytics and Technology reports into the Vice President Process Sciences and Analytics and Technology in the Cell Therapy business unit. The position will set the vision strategy and execution for automation robotics digital integration and technical writing across Process Sciences Analytics and Technology. This leader owns the multiyear capability buildspanning automated and closedsystem laboratory/pilot operations endtoend data connectivity process control and a bestinclass technical writing function that accelerates development and underpins robust technology transfer and regulatory success. The role partners with Process/Analytical Development MSAT Manufacturing Quality Digital/IT Supply Chain and Regulatory to drive portfolio impact shorten cycle times and enable reliable scaleup from preclinical through commercial readiness.

Responsibilities

• Define the multiyear strategy and target operating model for automation robotics digital connectivity and technical writing; align with platform and modality roadmaps.

• Establish and lead an integrated organization of automation/controls engineers robotics specialists data/OT engineers integration architects and technical writers; set governance prioritization and ensure project finance targets

• Oversee selection and deployment of closed and semiclosed automated unit operations robotics implementation and automated solution for QC analytics.

• Architect and deliver secure validated connectivity from bench and pilot instruments to enterprise platforms including:

  • System Integrations: Integrate instruments and controllers with ELN/LIMS MES/eBR SCADA/DCS data historians and data lake/warehouse; implement eventdriven and APIbased data flows with robust error handling and retries.

  • Define standard data models ontologies and metadata schemas for cell therapy unit operations; enforce FAIR principles and contextualization to enable analytics modeling and seamless tech transfer.

  • Partner with IT/Cyber to implement rolebased access control certificate management secure patching and vulnerability management across OT assets.

  • Deliver CSV for integrations and interfaces; ensure audit trails electronic signatures and data integrity (ALCOA) are designed in and tested; maintain change control for connectors and adapters.

  • Stand up observability (logging metrics alerting) connection health dashboards and SLAs for data latency and uptime; establish support models and incident response for OT/IT integrations.
    

• Technical Writing Center of Excellence: Build a COE delivering highquality protocols reports comparability packages work instructions and CMCsupporting content; standardize templates and review workflows to reduce cycle time and improve traceability.

• Compliance and CSV: Ensure GxP alignment data integrity and CSV for automated systems and digital interfaces; define SOPs training and inspection readiness; incorporate cybersecurity and business continuity requirements into design.

• Sequence and resource programs that reduce manual touch points increase throughput and enhance data reliability; track realized benefits to cycle time cost of goods and quality.

• Talent and Culture: Recruit and develop a multidisciplinary team; foster a culture of safety scientific rigor designforGMP and continuous improvement; lead change management and user adoption for new automated and connected workflows.

• CrossFunctional Influence: Serve as primary interface with PD leadership MSAT Manufacturing Operations Quality Digital/IT and Regulatory; represent the function in governance forums and relevant regulatory interactions.

Qualifications

• Education: Advanced degree in engineering (chemical biomedical electrical) computer science or related field; PhD preferred or MS with substantial industry experience.

• Experience: 1215 years in biopharma/biotech with 7 years leading automation/robotics and digital connectivity programs; direct experience in cell therapy or ATMPs strongly preferred; leadership across multisite/global organizations.

• Technical Expertise: Proven delivery of automated and closedsystem cell processing and lab robotics; deep familiarity with ELN/LIMS MES/eBR SCADA/DCS historians data lakes and integration patterns; experience with singleuse technologies aseptic/BSL2 and cleanroom constraints; understanding of AI/ML for process development is a plus.

• Strong grounding in GxP data integrity and CSV; experience supporting IND/BLA modules preapproval inspections and inspection readiness.

• Evidence of building or leading a technical writing function; mastery in authoring and reviewing complex development reports protocols comparability and tech transfer packages with clear traceability and scientific narrative.

• Track record of building highperforming teams setting strategy securing investment and influencing senior stakeholders across Development MSAT Manufacturing Quality and Digital/IT; adapt at change management and user adoption.

• Ability to quantify ROI define KPIs and make tradeoffs across cost speed and risk; skilled in vendor negotiations and longterm agreements.

• Exceptional communication stakeholder management and executive presence; structured problem solving and prioritization in fastpaced ambiguous environments.

• Reports to the Head/Vice President of Cell Therapy Process Development (or equivalent).

• Onsite leadership presence with laboratory and pilot facilities; hybrid flexibility for crossfunctional engagement.

When we put unexpected teams in the same room we fuel bold thinking with the power to inspire life-changing -person working gives us the platform we need to connect work at pace and challenge perceptions. Thats why we work on average a minimum of three days per week from the Santa Monica CA office. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

The annual base salary for this position ranges from $255000 to $380000. However base pay offered may vary depending on multiple individualized factors including market location job-related experience. If hired employee will be in an at-will position and we reserve the right to modify base salary (and any other discretionary payment or compensation program) at any time including for reasons related to individual performance Company or individual department/team performance and market factors.

Date Posted

Closing Date

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and furtherance of that mission we welcome and consider applications from all qualified candidates regardless of their protected characteristics. If you have a disability or special need that requires accommodation please complete the corresponding section in the application form.