The VIB-KU Leuven Center for Neuroscience Belgium is seeking a research technician to support a drug discovery project focused on RNA based therapies of Alzheimers disease. The candidate will work in a team of scientists dedicated to develop antisense oligonucleotides as disease-modifying therapeutics for neurodegenerative diseases. Our strategy is based on an innovative all-in-human discovery engine platform deep understanding of disease genetics and pathophysiology and experienced translational biology.
About the role
The research associate will be responsible for conducting both in vitro and in vivo experimental work in our Leuven laboratory supporting ongoing research projects through a variety of tasks. Daily responsibilities will include drug screening neuronal cell culture preparation and analysisa range of molecular biology techniques such as qPCR RT-qPCR Western blotting ELISA and immunofluorescence as well as mouse handling monitoring drug administration tissue collection and processing. The successful candidate will also have the opportunity to receive training and work with advanced technologiesincluding 3D cell culture systems and xenografted mouse models in a dynamic and collaborative research environment.
Your profile
General & Professional skills
You possess a degree in Biomedical or Biological Sciences (Professional Bachelor/Master/Engineer or equivalent)
Excellent organizational skills with the ability to manage multiple experiments independently
Strong attention to detail data integrity and scientific rigor
Proactive in adopting new techniques and technologies
Comfortable working independently and collaboratively in a multidisciplinary setting
Fluency in written and spoken English
Good understanding of early drug discovery and pharmacology concepts are a strong asset
In vitro skills
Solid background in cellular and molecular biology with hands-on experience in wet-lab workflows
Advanced cell culture experience including stem cell maintenance and differentiation
Experience with cell-based assays dose-response studies and plate-based screening in drug discovery contexts
Ability to optimize troubleshoot and ensure robustness of in-vitro assays
High level of proficiency in liquid handling experimental precision and assay reproducibility
Strong track record of accurate data generation documentation and experimental reporting
In vivo skills
FELASA B license for animal work is required.
Demonstrated experience in animal handling and working with rodent disease models
Familiarity with in vivo experimental procedures ethical guidelines and regulatory compliance
Ability to accurately document procedures observation and outcomes in line with SOPs.
Our offer
A stimulating diverse international and exceptionally strong research environment in a world-class academic laboratory with a focus on Alzheimers disease.
Access to state-of-the-art infrastructure.
A competitive compensation package taking into account expertise and work experience
Start date: as soon as possible - the position is available immediately
About usThe VIB-KU Leuven Center for Neuroscience Belgium is seeking a research technician to support a drug discovery project focused on RNA based therapies of Alzheimers disease. The candidate will work in a team of scientists dedicated to develop antisense oligonucleotides as disease-modifying th...
About us
The VIB-KU Leuven Center for Neuroscience Belgium is seeking a research technician to support a drug discovery project focused on RNA based therapies of Alzheimers disease. The candidate will work in a team of scientists dedicated to develop antisense oligonucleotides as disease-modifying therapeutics for neurodegenerative diseases. Our strategy is based on an innovative all-in-human discovery engine platform deep understanding of disease genetics and pathophysiology and experienced translational biology.
About the role
The research associate will be responsible for conducting both in vitro and in vivo experimental work in our Leuven laboratory supporting ongoing research projects through a variety of tasks. Daily responsibilities will include drug screening neuronal cell culture preparation and analysisa range of molecular biology techniques such as qPCR RT-qPCR Western blotting ELISA and immunofluorescence as well as mouse handling monitoring drug administration tissue collection and processing. The successful candidate will also have the opportunity to receive training and work with advanced technologiesincluding 3D cell culture systems and xenografted mouse models in a dynamic and collaborative research environment.
Your profile
General & Professional skills
You possess a degree in Biomedical or Biological Sciences (Professional Bachelor/Master/Engineer or equivalent)
Excellent organizational skills with the ability to manage multiple experiments independently
Strong attention to detail data integrity and scientific rigor
Proactive in adopting new techniques and technologies
Comfortable working independently and collaboratively in a multidisciplinary setting
Fluency in written and spoken English
Good understanding of early drug discovery and pharmacology concepts are a strong asset
In vitro skills
Solid background in cellular and molecular biology with hands-on experience in wet-lab workflows
Advanced cell culture experience including stem cell maintenance and differentiation
Experience with cell-based assays dose-response studies and plate-based screening in drug discovery contexts
Ability to optimize troubleshoot and ensure robustness of in-vitro assays
High level of proficiency in liquid handling experimental precision and assay reproducibility
Strong track record of accurate data generation documentation and experimental reporting
In vivo skills
FELASA B license for animal work is required.
Demonstrated experience in animal handling and working with rodent disease models
Familiarity with in vivo experimental procedures ethical guidelines and regulatory compliance
Ability to accurately document procedures observation and outcomes in line with SOPs.
Our offer
A stimulating diverse international and exceptionally strong research environment in a world-class academic laboratory with a focus on Alzheimers disease.
Access to state-of-the-art infrastructure.
A competitive compensation package taking into account expertise and work experience
Start date: as soon as possible - the position is available immediately