Senior Software Engineer, Variant Classification

Job Responsibilities:

• Design and build tools that define store and provide meaningful variant sample and test level information to supportaccuratevariant interpretation and report generation

• Develop andmaintainsystems that translate raw bioinformatic data into variant and sample level information including registration normalization observation groups and quality metrics

• Scale andoptimizestorage of sample level information to support growing data needs

• Sourcemaintain and provide annotations at the variant level necessary foraccuratevariant interpretation

• Automate evidence placement and classification for variant interpretation

• Support test content and assay development initiatives

• Collaborate with data scientists variant scientists and software developers to design and implement solutions that meet stakeholder requirements

Minimum Qualifications:

• Bachelors degreein Life SciencesCS Engineeringwith 5 years of recent professional software developmentexperience

• 5 or more years of recent experience with Python (intermediate level or higher)

• 5 or more years of recent experience with relational databases and web development frameworks

• 5 or more years of recent experience with front-end technologies (e.g. React Angular JavaScript/TypeScript HTML/CSS)

• 5 or more years of recent experience with RESTful APIs and microservices architecture

• 5 or more years of recent experience with CI/CD pipelines and DevOps practices

• 5 or more years of recent experience with cloud platforms (AWS Azure or GCP)

Preferred Qualifications:

• Masters degree or Ph.D. in Bioinformatics/Computational Biology or life sciences

• 3 or more years of experience with bioinformatic tools and annotation

• 3 or more years of experience with variant databases and genomic data resources (e.g.ClinVargnomAD HGMD)

• 3 or more years of experience in Spark text mining natural language processing semantic enrichment ontologies data mining or machine learning/AI

• 3 or more years of experience with public-domain biomedical terminologies (e.g.MeSHNCIt HGNC)

• 3 or more years of experience translating complex scientific questions into information solutions

• 3 or more years of experience mentoring junior developers

• 3 or more years of experience leading technical projects or serving as a technical lead

Additional Job Standards:

• Strong analytical mindset with keen attention to detail and the ability to tackle ambiguous problems

• Effective verbal and written communicator with both scientific and non-scientific audiences

• Highly organized: manages multiple projects defines clear operational processes and delivers on time with high quality

• Proventrack recordof owning end-to-end project delivery and driving cross-team or cross-discipline initiatives

• Mentors and develops teammates through guidance role modeling and knowledge sharing

• Deep understanding of business context and customer needs ensuring solutions move the needle for the organization

• Effectivewith GitHub Copilot ClaudeCodeor similar LLM tools to accelerate codingtestingand documentation.

AboutLabcorpGenetics
Labcorp Genetics (formerlyInvitae) is dedicated to bringing comprehensive genetic information into mainstream medicine to improve healthcare for billions of people. The Variant Classification team builds andmaintainsthe tools that define store and provide meaningful and detailed variant sample and test level information to supportaccuratevariant interpretation and report generation. Our services supportinterpretation reportingof genetic variants and assay development across a suite of critical platforms including SDS VDB ArgusiVEP Evidence ServiceMoonPy Cerebro Universal Transcript ArchiveSeqRepo and Assay CMS.

AtLabcorpwe have a passion for helping people live happy and healthy lives. Every day we provide vital information that helps our clients and patients understand their health. If you are passionate about helping people and have a drive for service thenLabcorpcould be a great next career step!

Application Window: 5/1/2026

Pay Range: $100K to $185K/yr

All job offers will bebased on a candidates skills and prior relevant experience applicabledegrees/certificationsas well as internal equity and market data.

LBP:The position is also eligible for an annual bonus under the Labcorp Bonus are payable based on corporate and/or business segment performance and are subject to individual performance modifiers.

Benefits:Employees regularly scheduled to work 20 or more hours per week are eligible for comprehensive benefits including: Medical Dental Vision Life STD/LTD 401(k) Paid Time Off (PTO) or Flexible Time Off (FTO) Tuition Reimbursement and Employee Stock Purchase PRN & Part Time employees regularly scheduled to work less than 20 hours are eligible toparticipatein the 401(k) Plan only. Employees who are regularly scheduled toworka 7 on/7 off schedule are eligible to receive all the foregoing benefits except PTO or FTO. For more detailed information pleaseclick here.