Director CfOR Operations

Career Category

Job Description

Join Amgens Mission of Serving Patients

At Amgen if you feel like youre part of something bigger its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do.

Since 1980 weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology Inflammation General Medicine and Rare Disease we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer heart disease inflammatory conditions rare diseases and obesity and obesity-related conditions. As a member of the Amgen team youll help make a lasting impact on the lives of patients as we research manufacture and deliver innovative medicines to help people live longer fuller happier lives.

Our award-winning culture is collaborative innovative and science based. If you have a passion for challenges and the opportunities that lay within them youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Director CfOR Operations

What you will do

Increasing demand for real-world evidence (RWE) from regulatory and reimbursement authorities has made observational research a critical driver of drug development access and lifecycle strategy. Amgens Center for Observational Research (CfOR) is a global industry-leading organization that generates high-impact RWE to inform key decisions across the product lifecycle. CfOR partners across R&D Medical and commercial functions to shape evidence strategies optimize clinical development and evaluate the value safety and effectiveness of Amgen therapies.

Lets do this. Lets change the this vital role you will lead the operational engine that enables the efficient scalable and compliant delivery of observational research across CfOR. You will be accountable for how work gets done across the organization driving the systems processes and cross-functional coordination required to improve throughput reduce cycle times and support high-quality evidence generation at scale.

You will lead a high-performing multi-functional team of 16 and partner closely with CfOR Product Leads and the Data & Analytic Center (DAC) leadership to ensure operational excellence across a complex global portfolio.

Key responsibilities

Operational Excellence & Scale

• Own and evolve core operational processes supporting observational research including contracting study start-up and close-out supplier governance and compliance workflows
• Drive measurable improvements in cycle time predictability and throughput across the portfolio
• Identify operational bottlenecks and implement scalable solutions including process standardization automation and tool adoption
• Establish structured project management approaches across workflows to improve planning execution and visibility

Financial & Resource Strategy

• Own core operational processes including headcount planning financial forecasting budget oversight and resource optimization
• Lead annual budgeting forecasting and quarterly Latest Estimates in partnership with Finance
• Oversee external workforce strategy supplier mix and resource capacity planning to align with portfolio demand
• Ensure disciplined financial management and accountability to budget targets

Cross-Functional Integration

• Serve as the primary operational interface across R&D Medical Finance Legal Procurement Quality and Compliance
• Drive alignment and resolve cross-functional dependencies to enable efficient execution
• Strengthen coordination between business and support functions to improve service delivery and reduce friction

Team Leadership & Performance

• Lead develop and scale a multi-functional team setting clear expectations for performance accountability and delivery
• Proactively identify and address performance gaps ensuring consistent execution and high-quality outputs
• Foster a culture of ownership continuous improvement and urgency balanced with thoughtful planning

Strategic Operations & Change Leadership

• Partner with the Head of CfOR Operations and senior leadership to evolve the operating model in response to growing demand and complexity
• Lead cross-functional initiatives to build new capabilities through technology automation and process innovation
• Act as a strategic thought partner bringing forward insights challenging assumptions and shaping operational strategy

Governance & Compliance

• Oversee development and implementation of policies SOPs and controlled documents
• Ensure adherence to regulatory and compliance requirements across all operational activities

What we expect of you

We are all different yet we all use our unique contributions to serve patients. The qualified professional we seek is a leader with these qualifications.

Basic Qualifications:

• Doctorate degree and 4 years of experience in operations or clinical studies or
• Masters degree and 8 years of experience or
• Bachelors degree and 10 years of relevant experience

Preferred Qualifications:

• 12 years of experience in biotechnology pharmaceutical healthcare or management consulting with increasing scope and responsibility
• Demonstrated track record of building scaling or transforming operational functions in complex matrixed environments
• Proven ability to drive measurable operational improvements (e.g. reduced cycle times increased throughput improved cost efficiency)
• Strong leadership experience with a focus on talent development performance management and team accountability
• Deep understanding of observational research and the drug development lifecycle across Research Development Regulatory and Medical
• Exceptional problem-solving skills with the ability to structure ambiguous challenges and implement practical scalable solutions
• Strong executive communication and stakeholder management skills with the ability to influence without authority
• Experience implementing digital tools automation and analytics to improve operational performance with the ability to evaluate and adopt emerging technologies including AI
• High degree of ownership learning agility and adaptability in a fast-paced evolving environment

What you can expect of us

As we work to develop treatments that take care of others we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture well support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to relevant skills experience and qualifications.

In addition to the base salary Amgen offers a Total Rewards Plan based on eligibility comprising of health and welfare plans for staff and eligible dependents financial plans with opportunities to save towards retirement or other goals work/life balance and career development opportunities that may include:

• A comprehensive employee benefits package including a Retirement and Savings Plan with generous company contributions group medical dental and vision coverage life and disability insurance and flexible spending accounts
• A discretionary annual bonus program or for field sales representatives a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

Apply now and make a lasting impact with the Amgen team.

In any materials you submit you may redact or remove age-identifying information such as age date of birth or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Sponsorship

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world Amgen fosters an inclusive environment of diverse ethical committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race color religion sex sexual orientation gender identity national origin protected veteran status disability status or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process to perform essential job functions and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Salary Range