Associate Scientist, Cell Biology

Were here for one reason and one reason only to cure cancer. Every moment is dedicated to developing treatments and every action moves us one step closer to our goal. Weve made incredible scientific breakthroughs and our pioneering personalized CAR T-cell therapies have changed the paradigm. But were not finished yet.

Join Kite as we make even bigger advances in cancer therapies and help shape where our business and medical science goes next.

We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future you are the key driver in evolving our culture and creating an environment where every employee feels included developed and empowered to fulfil their aspirations. Join Kite and help create more tomorrows.

Job Description

AtGileadour pursuit of a healthier world for all people has yielded a cure for hepatitis C revolutionary improvements in HIV treatment and prevention as well as advancements in therapies for viral and inflammatory diseases and certain cancers.

We set and achieve bold ambitions in our fight against the worlds most devastating diseases united in our commitment to confronting the largest public health challenges of our day and improving the lives of patients for generations to come.

Were here for one reason and one reason only to cure cancer. Every moment is dedicated to developing treatments and every action moves us one step closer to our goal. Weve made incredible scientific breakthroughs and our pioneering personalized CAR T-cell therapies have changed the paradigm. But were not finished yet.

Join Kite as we make even bigger advances in cancer therapies and help shape where our business and medical science goes next.

We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future you are the key driver in evolving our culture and creating an environment where every employee feels included developed and empowered to fulfil their aspirations. Join Kite and help create more tomorrows.

Job Description
We are seeking a highly motivated Associate Scientist to join our In Vivo Discovery team focused on developing targeted vectors to reprogram cells in vivo for the treatment of cancer. This individual will drive hands-on execution of small animal model studies and complementary in vitro experiments (e.g. routine cell culture and cell-based assays) to evaluate experimental constructs and connect mechanistic findings to in vivo outcomes. The successful candidate brings strong critical thinking and scientific judgment operates with high integrity and is comfortable flexing between mouse work and bench-based assays planning experiments against timelines troubleshooting technical challenges and generating high-quality reproducible data while following research protocols and SOPs with precision and consistency.

The successful candidate will function as an individual scientific contributor comfortable with interactions at all levels in the organization be a quick learner detail-oriented multi-tasker self-reliant problem-solving scientist with utmost integrity and excellent interpersonal skills who is able to contribute to a dynamic exciting culture that embraces teamwork and innovation.

Job Responsibilities

• Plan and execute experiments (in vivo and in vitro) against project timelines goals and study endpoints; coordinate day-to-day study logistics as needed.

• Lead and execute hands-on in vivo mouse studies including routine animal handling dosing/injections (e.g. intravenous tail vein and intraperitoneal as applicable) IVIS imaging support blood collection tissue harvest/dissection and sample processing in accordance with approved protocols and SOPs.

• Design perform and optimize complementary in vitro experiments (e.g. routine mammalian cell culture primary human cell handling and cell-based assays) to evaluate experimental constructs and connect in vitro findings to in vivo outcomes; engineer culture and characterize CAR T cells in vitro as needed.

• Support immunophenotyping and biomarker readouts including flow cytometry (with appropriate training/supervision); analyze results and translate findings into actionable next steps.

• Set up and run ELISA and other plate-based assays analyze and interpret data with attention to quality and reproducibility and present results in team meetings.

• Independently troubleshoot and optimize in vivo procedures and in vitro assays using critical thinking and scientific judgment to reduce variability and improve robustness.

• Collaborate with cross-functional partners to align study plans sample logistics and data outputs with program objectives; summarize findings in clear technical updates and presentations.

• Contribute to a positive high-performing team culture by sharing best practices and mentoring/training junior staff in mouse study execution assay performance data analysis and laboratory organization.

• Maintain mammalian cell lines and primary human cells using sterile technique in a biosafety cabinet.

• Organize and maintain experimental work in an electronic lab notebook.

• Occasional weekend work might be required.

Basic Requirements

• Masters and 2 years of relevant experience

OR

• Bachelors and 4 years of relevant experience

Preferred Qualifications

• Degree in Immunology or Cell Biology is preferred.

• 4 years experience in an academic or industry setting is preferred.

• Prior experience mouse handling and interventions including intravenous (tail vein) and intraperitoneal injections are highly preferred.

• Demonstrated critical thinking and scientific judgment with a track record of independently troubleshooting and optimizing methods to deliver high-quality reproducible data.

• Ability to flex seamlessly between hands-on mouse studies and bench-based in vitro experiments adapting daily priorities to meet program needs and study schedules.

• Experience with mammalian cell culture and primary cells is ideal.

• Strong organizational skills attention to detail and commitment to highquality data generation.

• Proficiency in Excel PowerPoint Prism and other programs to create and distribute reports and key information

• Excellent interpersonal written and verbal communication skills

• Ability to work onsite in a laboratory environment

For additional benefits information visit:

Eligible employees may participate in benefit plans subject to the terms and conditions of the applicable plans.

Kite is a biopharmaceutical company engaged in the development of innovative cancer immunotherapies with a goal of providing rapid long-term durable response and eliminating the burden of chronic care. The company is focused on chimeric antigen receptor (CAR) and T cell receptor (TCR) engineered cell therapies designed to empower the immune systems ability to recognize and kill tumors. Kite is based in Santa Monica CA. For more information on Kite please visit . Sign up to follow @KitePharma on Twitter at jobs in the United States:

Kite Pharma is committed to providing equal employment opportunities to all employees and applicants for employment and is dedicated to fostering an inclusive work environment comprised of diverse perspectives backgrounds and experiences. Employment decisions regarding recruitment and selection will be made without discrimination based on race color religion national origin sex age sexual orientation physical or mental disabilitygenetic information or characteristic gender identity and expression veteran status or other non-job related characteristics or other prohibited grounds specified in applicable federal state and local order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973 the Vietnam Era Veterans Readjustment Act of 1974 and Title I of the Americans with Disabilities Act of 1990 applicants who require accommodation in the job application process may contact for assistance.

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Kite Pharma will not discharge or in any other manner discriminate against employees or applicants because they have inquired about discussed or disclosed their own pay or the pay of another employee or applicant. However employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information unless the disclosure is (a) in response to a formal complaint or charge (b) in furtherance of an investigation proceeding hearing or action including an investigation conducted by the employer (c) consistent with the legal duty to furnish information; or (d) otherwise protected by law.

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Kite Pharma provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion.

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