Facilities Maintenance Supervisor

AstraZeneca

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profile Job Location:

Los Angeles, CA - USA

profile Monthly Salary: $ 89874 - 134812
Posted on: 8 hours ago
Vacancies: 1 Vacancy

Job Summary

Position Summary:

The Facilities Maintenance Supervisor leads maintenance operations to ensure the safe compliant and highly reliable performance of critical manufacturing and facility systems supporting cell therapy production in Tarzana a Cell Therapy environment where products are often patient-specific and time-sensitive this role is critical to maintaining uninterrupted operations cleanroom conditions and strict chain-of-identity and chain-of-custody controls Tarzana CA. The role integrates reliability engineering principles with daily maintenance execution focusing on eliminating repeat failures reducing unplanned downtime and improving asset lifecycle performance in a highly regulated environment governed by FDA expectations and advanced therapies guidelines.

Success in this role requires the ability to:
Lead teams in a fast paced patient-centric manufacturing environment
Balance speed compliance and precision
Anticipate and mitigate risks to critical often irreplaceable batches
Drive transition from reactive to predictive maintenance strategies
Collaborate multi-functionally with Manufacturing Quality and Engineering to support 7 days cell therapy operations


Ultimately the Maintenance Supervisor plays a direct role in ensuring that life-saving therapies reach patients safely reliably and on time by maintaining the integrity and performance of the systems that produce them.

Responsibilities:

  • Leadership & Team Management: Manage and mentor maintenance technicians; set clear expectations for safety quality and performance; lead daily tier meetings and shift handovers; build a culture of ownership urgency and continuous improvement; collaborate with Engineering Quality and Operations.

  • Maintenance Execution & Compliance: Ensure all activities meet GMP FDA and site standards; review and approve complete accurate work orders; enforce CMMS usage (e.g. SAP); lead aspects of preventive and corrective maintenance and calibrations; maintain inspection readiness and support audits.

  • Reliability & Asset Management: Implement reliabilitycentered maintenance; investigate failures using RCA and FMEA; improve MTBF and MTTR; identify and resolve bad actor equipment; partner on upgrades and lifecycle management.

  • Planning & Scheduling: Work with the Maintenance Planner to prioritize and schedule work; secure parts tools and permits in advance; validate and refine job plans; increase labor efficiency and minimize reactive work.

  • Safety Health and Environment (SHE): Enforce LOTO confined space and permit systems; conduct safety observations audits and incident investigations; lead by example to sustain a zeroincident culture.

  • Continuous Improvement: Remove waste from maintenance processes; increase schedule compliance PM efficiency and spareparts management performance; lead or participate in Kaizen and Lean initiatives.

  • Work Environment: AZ is a cGMP regulated pharmaceutical manufacturing facility. We require your presence on the production floor and occasional off-shift support This may involve gowning for cleanroom environments

Minimum requirements:

  • High school diploma/GED required.
    8 years in industrial facilities maintenance/leadership experience

  • 4 years of leadership experience in a pharmaceutical biotech or GMP regulated environment (medical device/food service may be acceptable.)

Desirable:

  • Technical diploma/apprenticeship in HVAC or Boiler maintenance.

  • Bachelors degree in Mechanical engineering or Facilities Management is a plus.

    .

The annual base salary for this position ranges from $89874 to $134812. However base pay offered may vary depending on multiple individualized factors including market location job-related knowledge skills and addition our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles) to receive a retirement contribution (hourly roles) and commission payment eligibility (sales roles).

Our Benefits:

Benefits offered include:

  • A qualified retirement program 401(k) plan

  • Paid vacation holidays and paid leaves

  • Health benefits including medical prescription drug dental and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment.

#celltherapy

Date Posted

23-Apr-2026

Closing Date

07-May-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and furtherance of that mission we welcome and consider applications from all qualified candidates regardless of their protected characteristics. If you have a disability or special need that requires accommodation please complete the corresponding section in the application form.


Required Experience:

Manager

Position Summary: The Facilities Maintenance Supervisor leads maintenance operations to ensure the safe compliant and highly reliable performance of critical manufacturing and facility systems supporting cell therapy production in Tarzana a Cell Therapy environment where products are often patient-...
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AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, ... View more

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