Associate Scientist, In vivo Pharmacology, Inflammation

Career Category

Job Description

Join Amgens Mission of Serving Patients

At Amgen if you feel like youre part of something bigger its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do.

Since 1980 weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology Inflammation General Medicine and Rare Disease we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer heart disease inflammatory conditions rare diseases and obesity and obesity-related conditions. As a member of the Amgen team youll help make a lasting impact on the lives of patients as we research manufacture and deliver innovative medicines to help people live longer fuller happier lives.

Our award-winning culture is collaborative innovative and science based. If you have a passion for challenges and the opportunities that lay within them youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Associate Scientist In vivo Pharmacology Inflammation

What you will do

Lets do this. Lets change the this vital role you will work in a highly dynamic in vivo pharmacology team executing in vivo preclinical disease models and in vitro assays in the vivarium and lab supporting pipeline programs.

Key Responsibilities:

• Perform hands-on in vivo work primarily mice possibly rats in the vivarium daily.
• Provide technical support for studies dosing sample/tissue collection health checks study setup and take down.
• Work side-by-side with Scientists/Senior Scientists to execute and help design experiments.
• Run concurrent studies stay organized and detail-oriented to meet study timelines
• Participate in weekend/evening dosing rotations as needed
• Support in vitro assays as required
• Communicate results to immediate team and follow established protocols and safety procedures
• Work in a flexible team-oriented environment. Weekend and evening work may be required.

What we expect of you

We are all different yet we all use our unique contributions to serve patients. The Associate Scientist we seek is a driven pro-active independent and enthusiastic scientist who wants to contribute to cutting edge science and serve patients in a highly productive team environment with these qualifications.

Basic Qualifications:

Masters degree and 1 year of Immunology or related experience

OR

Bachelors degree and 3 years of Immunology or related experience

Preferred Qualifications:

• M.S. degree in Immunology or related disciplines or B.S. degree with commensurate scientific / drug discovery experience and track record of scientific excellence and productivity.
• Strong understanding of Immunology and Inflammation biology and principles.
• Willingness and curiosity to learn and explore new areas of research.
• Significant experience designing and executing concurrent in vivo preclinical inflammation and autoimmune disease models. Experience with colitis (DSS CD45RBhi T cell transfer IL-10 KO) lupus (NZB/W MRL-lpr Imiquimod) and arthritis (CIA CAIA) GvHD models preferred. Experience in Asthma COPD HS PBC a plus.
• Hands-on experience with in vivo techniques including dosing route of administration (i.v. i.p. p.o. i.n. i.t. r.o. i.d. s.c.) bleeds (r.o. cheek tail) necropsy (organ collection (intestine/colon lung lymphnodes spleen liver kidney skin) cardiac bleed lung BAL collection).
• Hands-on experience in cellular biochemical histological and molecular biology assay techniques (i.e. ELISA MSD quantitative RT-PCR BCA protein measurements) preferred. Hands-on experience with multicolor flow cytometry including Spectral flow approaches and Immune cell populations is essential.
• Computer literacy especially proficiency with GraphPad Prism Excel PowerPoint and Word.
• Attention to detail excellent organizational and communication skills accurate & timely record keeping and data analysis are essential.
• Demonstrated track record of independent critical thinking and scientific achievement.
• Demonstrated experience in pharmacology and in vivo models of inflammation/Immunology.

What you can expect of us

As we work to develop treatments that take care of others we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture well support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to relevant skills experience and qualifications.

In addition to the base salary Amgen offers a Total Rewards Plan based on eligibility comprising of health and welfare plans for staff and eligible dependents financial plans with opportunities to save towards retirement or other goals work/life balance and career development opportunities that may include:

• A comprehensive employee benefits package including a Retirement and Savings Plan with generous company contributions group medical dental and vision coverage life and disability insurance and flexible spending accounts
• A discretionary annual bonus program or for field sales representatives a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

Apply now and make a lasting impact with the Amgen team.

In any materials you submit you may redact or remove age-identifying information such as age date of birth or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Sponsorship

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world Amgen fosters an inclusive environment of diverse ethical committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race color religion sex sexual orientation gender identity national origin protected veteran status disability status or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process to perform essential job functions and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Salary Range