Computational Biologist

Job Family:

Travel Required:

Clearance Required:

What You Will Do:
We are seeking a Biologist to support research on laboratory and computational analysis of genomic and epigenomic data. The work supports ongoing research involving genotyping long-range sequencing and DNA methylation profiling. This is a full-time opportunity located in Baltimore MD.

Responsibilities:

• Perform DNA extraction from blood tissue or cultured cells using established protocols.

• Conduct genotyping assays (e.g. SNP arrays PCR-based methods.

• Support long-range sequencing workflows (e.g. library prep and sequencing using long-read platforms such as PacBio or Oxford Nanopore).

• Provide technical support for biological research by assisting in the study of fundamental principles of plant and animal life including sample quality integrity coverage and contamination assessment.

• Evaluate biological data and quality control metrics flag anomalies and provide preliminary interpretations to research staff.

• Perform basic laboratory experiments including DNA methylation assays (e.g. bisulfite conversion and array or sequencingbased methods) following established protocols.

• Execute and support quality control pipelines for sequencing and genotyping data; compile document and maintain QC metrics in standardized formats.

• Conduct data analysis using established tools and methods including R for statistical analysis and visualization and scripting languages (e.g. Python Bash) for pipeline support.

• Modify and adapt existing scripts and analytical pipelines to meet projectspecific requirements and support data integration efforts.

• Prepare organize and maintain laboratory samples supplies and equipment ensuring accurate laboratory records notebooks and electronic documentation.

• Prepare summary tables figures and written descriptions of methods and results; present findings in internal meetings and contribute to draft reports manuscripts and project updates.

What You Will Need:

• Masters degree

• Minimum of FOUR (4) years of experience in biology or a related field performing biological research functions in a research setting.

• R/Python/Bash scripts experience.

• Experience modifying maintaining or executing existing analysis scripts and pipelines to support projectspecific research needs.

• Experience compiling QC metrics maintaining accurate laboratory notebooks and electronic records and preparing summary tables figures and written descriptions of methods and results

• Experience identifying routine technical issues applying standard troubleshooting approaches and learning new laboratory or analytical techniques as required

• Must be able to obtain and maintain a Federal or DoD Public Trust. Candidates must receive approved adjudication of their Public Trust prior to onboarding with Guidehouse. Candidates with an active Public Trust or existing suitability are preferred.

What Would Be Nice To Have:

• Proficiency in one scripting language

• Familiarity with genomic data formats (FASTQ BAM VCF)

What We Offer:

Guidehouse offers a comprehensive total rewards package that includes competitive compensation and a flexible benefits package that reflects our commitment to creating a diverse and supportive workplace.

Benefits include:

• Medical Rx Dental & Vision Insurance

• Personal and Family Sick Time & Company Paid Holidays

• Parental Leave

• 401(k) Retirement Plan

• Group Term Life and Travel Assistance

• Voluntary Life and AD&D Insurance

• Health Savings Account Health Care & Dependent Care Flexible Spending Accounts

• Transit and Parking Commuter Benefits

• Short-Term & Long-Term Disability

• Tuition Reimbursement Personal Development Certifications & Learning Opportunities

• Employee Referral Program

• Corporate Sponsored Events & Community Outreach

• annual membership

• Employee Assistance Program

• Supplemental Benefits via Corestream (Critical Care Hospital Indemnity Accident Insurance Legal Assistance and ID theft protection etc.)

• Position may be eligible for a discretionary variable incentive bonus

About Guidehouse

Guidehouse is an Equal Opportunity EmployerProtected Veterans Individuals with Disabilities or any other basis protected by law ordinance or regulation.

Guidehouse will consider for employment qualified applicants with criminal histories in a manner consistent with the requirements of applicable law or ordinance including the Fair Chance Ordinance of Los Angeles and San Francisco.

If you have visited our website for information about employment opportunities or to apply for a position and you require an accommodation please contact Guidehouse Recruiting at 1- or via email at . All information you provide will be kept confidential and will be used only to the extent required to provide needed reasonable accommodation.

All communication regarding recruitment for a Guidehouse position will be sent from Guidehouse email domains including @ or . Correspondence received by an applicant from any other domain should be considered unauthorized and will not be honored by Guidehouse. Note that Guidehouse will never charge a fee or require a money transfer at any stage of the recruitment process and does not collect fees from educational institutions for participation in a recruitment event. Never provide your banking information to a third party purporting to need that information to proceed in the hiring process.

If any person or organization demands money related to a job opportunity with Guidehouse please report the matter to Guidehouses Ethics Hotline. If you want to check the validity of correspondence you have received please contact . Guidehouse is not responsible for losses incurred (monetary or otherwise) from an applicants dealings with unauthorized third parties.

Guidehouse does not accept unsolicited resumes through or from search firms or staffing agencies. All unsolicited resumes will be considered the property of Guidehouse and Guidehouse will not be obligated to pay a placement fee.