Principal Enterprise Architect AI & Agents

IQVIA

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profile Job Location:

Durham, NC - USA

profile Monthly Salary: $ 118100 - 328800
Posted on: 6 days ago
Vacancies: 1 Vacancy

Job Summary

Job Summary

Within IQVIAs AI & Technology Solutions (ATS) organization the Architecture & Standards (A&S) group definesthe IQVIA wayof building technology. The Enterprise Architecture (EA) function operating within A&S is responsible for translating business strategy and OKRs into scalable standardsdriven architectures that reduce technical debt enable reuse and transform business processes.

The Enterprise Architecture organization is seeking aPrincipal Enterprise Architect AI & Agentic Solutionsto define govern and evolve enterprise architecture strategy standards and roadmaps across a large global technology landscape. This role plays a critical leadership position in shaping how AI and agentic capabilities are designed governed and adopted across IQVIA.

The ideal candidate combines strategic vision with architectural rigor. They understand how emerging AI technologies can reshape research and data operations within a CRO environment while ensuring alignment with enterprise principles governance and compliance requirements. This leader balances innovation with pragmatism and can translate complex AI concepts into structured capabilities reference architectures and reusable patterns. The role requires comfort engaging across engineering data science and senior business stakeholders to deliver responsible scalable and standardsdriven enterprise AI solutions.

Job Overview

The Principal Enterprise Architect is accountable for codesigning targetstate architectures and reference models for AI and agentic solutions establishing enterprise guardrails (patterns standards and decision frameworks) and providing architectural oversight for priority initiatives.

This role maintains a portfoliowide perspective of business and technical capabilities identifying crosscutting needs and opportunities to consolidate platforms and services across application and data domains. The Architect champions interoperability and reuse through modern architectural approaches cloudnative delivery and modern data platforms deployed on Azure and AWS.

What success looks like:

Published and broadly adopted AI and agent reference architectures

  • Increased reuse of shared services patterns and templates
  • Reduced duplication of AI implementations and development efforts
  • Faster architecture reviews and approvals with fewer exceptions
  • Improved compliance readiness for regulated and highrisk AI workloads

Key Responsibilities

Define maintain and evolve enterprise reference architectures standards and reusable patterns for generative AI and agentic systems.

  • Govern solution designs including selection of appropriate technical components ensuring delivery teams can adopt standards with minimal friction.
  • Provide architectural oversight for major AI initiatives guiding tradeoffs across security compliance scalability cost and timetovalue.
  • Translate business strategies and OKRs into capabilitybased roadmaps and targetstate architectures avoiding projectspecific point solutions.
  • Drive enterprise interoperability across systems and data domains by defining integration patterns and data exchange approaches aligned with enterprise standards.
  • Partner with compliance risk and information security teams to ensure architectures align with global regulatory and quality expectations (e.g. GxP GDPR HIPAA EU AI Act).
  • Maintain enterprise capability models and architecture artifacts using EA tools (e.g. LeanIX Ardoq MEGA) mapping capabilities to processes systems products outcomes and key data domains.
  • Identify opportunities to consolidate platforms and services across business units quantifying investment implications and business benefits.
  • Guide senior stakeholders through architectural options tradeoffs and investment decisions using clear businessfocused narratives and models.
  • Monitor AI agentic and life sciences technology trends; assess relevance and fit; and inform enterprise roadmaps reference architectures and innovation priorities.
  • Mentor and influence architects and senior engineers to raise overall architecture maturity and adherence to enterprise standards.

Required Qualifications

10 years of experience in enterprise or application architecture within large complex organizations including ownership of standards roadmaps and governance.

  • Proven experience designing and scaling generative AI and agentic solutions with a strong focus on reusable patterns and operationalization.
  • Deep technical knowledge of generative AI and agentic concepts including vector databases RAG tooluse MCP servers HITL evaluation frameworks monitoring observability and platforms such as LangGraph.
  • Strong cloud architecture experience on Azure and/or AWS including modern data architectures (lakehouse governance cataloguing).
  • Expertise in modern integration styles (APIfirst eventdriven microservices) and the ability to codify them into enterprise standards and reference architectures.
  • Exceptional communication influence and stakeholder management skills including engagement with senior business product and technology leaders.
  • Experience building business cases for modernization rationalization and platform consolidation initiatives.

Preferred Qualifications

Experience in healthcare or life sciences with strong knowledge of the clinical trial lifecycle realworld evidence or commercialization of clinical assets.

  • Handson partnership with CRO business teams including study design site activation and management clinical operations regulatory affairs medical affairs and KOL engagement realworld safety and efficacy pharmacovigilance and EMR ecosystems.
  • Proficiency with enterprise architecture tools (LeanIX Ardoq MEGA or similar) and formal capability modeling methodologies.

IQVIA is a leading global provider of clinical research services commercial insights and healthcare intelligence to the life sciences and healthcare industries. We create intelligent connections to accelerate the development and commercialization of innovative medical treatments to help improve patient outcomes and population health worldwide. Learn more at

IQVIA is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race color religion sex sexual orientation gender identity national origin disability status as a protected veteran or any other status protected by applicable law. is committed to integrity in our hiring process and maintains a zero tolerance policy for candidate fraud. All information and credentials submitted in your application must be truthful and complete. Any false statements misrepresentations or material omissions during the recruitment process will result in immediate disqualification of your application or termination of employment if discovered later in accordance with applicable law. We appreciate your honesty and professionalism.

The potential base pay range for this role when annualized is $118100.00 - $328800.00. The actual base pay offered may vary based on a number of factors including job-related qualifications such as knowledge skills education and experience; location; and/or schedule (full or part-time). Dependent on the position offered incentive plans bonuses and/or other forms of compensation may be offered in addition to a range of health and welfare and/or other benefits.

Required Experience:

Staff IC

Job SummaryWithin IQVIAs AI & Technology Solutions (ATS) organization the Architecture & Standards (A&S) group definesthe IQVIA wayof building technology. The Enterprise Architecture (EA) function operating within A&S is responsible for translating business strategy and OKRs into scalable standardsd...
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IQVIA is the Human Data Science Company™. We are inspired by the industry we serve and provide solutions that enable life sciences companies to innovate with confidence, maximize opportunities and ultimately drive human health outcomes forward. Our approach is Human Data Science – a d ... View more

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