(Senior) Scientist, Machine Learning

Build Models Where None Exist Yet.

At Flagship Pioneering we create companies from first principles. Within Flagship Labs small founding teams define new technical theses test them rapidly and build ventures around breakthrough ideas.

We are forming a machine learning team inside a newly launched venture Flagship Labs 120. Our work focuses on extracting latent structure from information-rich measurements of complex physical systemsoften requiring mechanism-informed modeling thoughtful inductive bias design and principled approaches to inverse problems.

This is a zero-to-one role focused on modeling innovation rather than routine optimization. Youll design prototype test and refine new approaches that help define the technical foundation of a platform from day one.

What Youll Do

• Develop and iterate on ML models for complex measurement data from representation design through validation
• Design objectives and architectures that respect known constraints symmetries or latent structure in the data
• Explore and compare modeling strategies balancing strong baselines with more experimental approaches when appropriate
• Investigate model behavior and failure modes to improve robustness and interpretability
• Collaborate closely with experimental and technical teammates to align modeling with data generation
• Contribute to shaping the long-term ML strategy and technical direction of a new venture

Who You Are

You may come from physics applied mathematics engineering computer science or another quantitative field. You have hands-on experience developing machine learning modelsideally in deep learning representation learning probabilistic modeling or related areas. You are comfortable implementing and modifying models training them end-to-end and working directly with real data.

You likely:

• Think algorithmically and reason from underlying structure
• Are comfortable adapting or extending model architectures when needed
• Have built and debugged meaningful ML systems or research prototypes
• Enjoy operating in dynamic early-stage environments
• Read papers build prototypes to test ideas and translate concepts into working systems

What matters most is your ability to reason across data models and the systems they represent.

Technical Background

• Strong hands-on experience building and training modern ML models
• Fluency in Python and at least one major ML framework (e.g. PyTorch or equivalent)
• Experience working with real-world or experimentally generated data
• Ability to design run and interpret ML experiments
• Comfort working in practical development environments (e.g. cloud infrastructure experiment tracking reproducible workflows)

Helpful

• Experience with inverse problems latent-variable inference or structured generative modeling (e.g. diffusion or flow-based methods)
• Familiarity with geometric or symmetry-aware architectures
• Experience incorporating physical or structural constraints into learning systems
• Experience working with time-series or high-dimensional signal data
• Exposure to biology chemistry physics or related sciences

ABOUT FLAGSHIP PIONEERING

Flagship Pioneering invents and builds platform companies each with the potential for multiple products that transform human health sustainability and beyond. Since its launch in 2000 Flagship has originated more than 100 companies. Many of these companies have addressed humanitys most urgent challenges: vaccinating billions of people against COVID-19 curing intractable diseases improving human health preempting illness and feeding the world by improving the resiliency and sustainability of agriculture.

Flagship has been recognized twice on FORTUNEs Change the World list an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Companys annual list of the Worlds Most Innovative Companies. Learn more about Flagship at.

At Flagship we accept impossible missions to enable bigger leaps. Ourcore values guide us through uncertainty and toward lasting impact.

We are an equal opportunity employer. All qualified applicants will be considered for employment without regard to race color religion sex sexual orientation gender identity national origin disability protected veteran status or any other characteristic protected by law.

We recognize that great candidates often bring unique strengthswithout fulfilling every qualification. If you have some of the experience listed above but not all please apply anyway. We are dedicated to building diverse and inclusive teams and look forward to learning more about your backgroundand interest in Flagship.

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively FSP) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneerings internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP and FSP will not owe any referral or other fees with respect thereto.

The salary range for this role is $130000 - $230000. Compensation for the role will depend on a number of factors including a candidates qualifications skills competencies and experience. FL120 currently offers healthcare coverage annual incentive program retirement benefits and a broad range of other benefits. Compensation and benefits information is based on FL120s good faith estimate as of the date of publication and may be modified in the future.

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