Senior Manager, Vector Biology

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About Innovative Medicine

Our expertise in Innovative Medicine is informed and inspired by patients whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments finding cures and pioneering the path from lab to life while championing patients every step of the way.

Learn more at are searching for the best talent for a Senior Manager Vector Biology to be in Cambridge MA.

Purpose:

We are seeking an experienced Senior Manager to oversee a multidisciplinary team responsible for advancing viral vector biology vector design improvements assay development and optimization of lentiviral vectors for in vivo cell this role you will provide technical leadership and strategic direction to drive the teams research and development efforts with a focus on enhancing cell-specific transduction capabilities.

You will be responsible for:

• Manage a team of scientists and engineers focused on viral vector biology vector design and assay development

• Oversee the teams work to improve lentiviral vector design and performance for in vivo cell targeting including:

  • Identifying optimal target molecules and cell surface receptors for efficient vector binding and entry

  • Leveraging expertise in cell biology to understand and enhance vector-cell interactions for improved cell type-specific transduction

  • Designing and validating assays to characterize vector tropism cell binding internalization and transduction efficiency

• Develop and implement strategies to optimize lentiviral vectors for specific cell type transduction

• Ensure the team designs and validates robust assays to test key assumptions about vector biology cell targeting and overall performance

• Collaborate cross-functionally with other R&D teams to integrate vector innovations into cell and gene therapy programs

• Provide technical leadership and strategic direction to drive the teams research and development efforts

• Manage budgets timelines and resources to deliver on team objectives

• Foster a culture of innovation continuous improvement and strong scientific rigor

Qualifications:

• Advanced degree (PhD preferred) in molecular biology virology bioengineering or a related field with 6-8 years of relevant industry experience in cell and gene therapy with a strong background in viral vector development

• Deep expertise in lentiviral vector biology design and optimization for in vivo applications including strong knowledge of cell biology principles to enable efficient cell targeting

• Extensive experience developing and validating assays to characterize vector tropism cell binding internalization and transduction efficiency

• Demonstrated track record of leveraging cell biology insights to engineer improved cell-targeting capabilities of viral vectors

• Thorough understanding of cell surface receptor biology cell signaling pathways and intracellular trafficking mechanisms to inform vector design and optimization

• Proven track record of leading multidisciplinary teams and delivering tangible R&D outcomes

• Excellent problem-solving project management and communication skills

• Ability to translate complex scientific concepts including cell biology into actionable strategies

• Strong collaborative mindset and ability to work effectively cross-functionally

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race color religion sex sexual orientation gender identity age national origin disability protected veteran status or other characteristics protected by federal state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson and Johnson is committed to providing an interview process that is inclusive of our applicants needs. If you are an individual with a disability and would like to request an accommodation please email the Employee Health Support Center () or contact AskGS to be directed to your accommodation resource.

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The anticipated base pay range for this position is :

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Senior Manager